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IMP + NAD+
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
inosine 5'-diphosphate + NAD+ + H2O
xanthosine 5'-diphosphate + NADH + H+
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
additional information
?
-
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
Q81W29
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-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
rate-limiting enzyme in the de novo purine biosynthetic pathway leading to the formation of guanine ribonucleotides
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-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
rate-limiting enzyme in the de novo purine biosynthetic pathway leading to the formation of guanine ribonucleotides
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
r
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
?
IMP + NAD+ + H2O
XMP + NADH + H+
-
-
-
-
?
inosine 5'-diphosphate + NAD+ + H2O
xanthosine 5'-diphosphate + NADH + H+
-
-
-
?
inosine 5'-diphosphate + NAD+ + H2O
xanthosine 5'-diphosphate + NADH + H+
-
xanthosine 5'-diphosphate is the only product
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
-
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
subdomain of the enzyme is not required for catalytic activity
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
-
-
r
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
-
-
r
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
-
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
the enzyme is important for the synthesis of guanine nucleotides
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
-
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
-
-
-
ir
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
rate-limiting step of the de novo guanine nucleotide biosynthesis
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
-
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
-
-
-
r
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
rate-limiting step of the de novo guanine nucleotide biosynthesis
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
rate-limiting step of the de novo guanine nucleotide biosynthesis
-
-
ir
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
the enzyme performs the rate-limiting step in guanine nucleotide biosynthesis
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
obligatory step in biosynthesis of nucleic acid guanine
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
Parainfluenza virus
-
rate-limiting step of the de novo guanine nucleotide biosynthesis, pathway overview
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
enzyme linked to proliferation and malignancy
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
rate-limiting step of the de novo guanine nucleotide biosynthesis
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
the reaction is irreversible over the range of pH 5.5 to pH 8.8, step in guanylic acid biosynthesis
-
-
ir
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
-
-
-
r
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
rate-limiting step of the de novo guanine nucleotide biosynthesis
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
rate-limiting step of the de novo guanine nucleotide biosynthesis, pathway overview
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
rate-limiting step of the de novo guanine nucleotide biosynthesis, pathway overview
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
-
-
-
?
inosine 5'-phosphate + NAD+ + H2O
xanthosine 5'-phosphate + NADH
-
IMP oxidation is the predominant metabolic route leading to ureide synthesis
-
-
?
additional information
?
-
-
enzyme inhibition by mycophenolic acid impairs maturation and function of dendritic cells due to low GTP levels and reduced expression of CD80, CD40, CD86, CD54, and CD83 in dendritic cells, accompanied by a decreased capacity to stimulate T-lymphocytes
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-
?
additional information
?
-
enzyme mutations are involved in autosomal dominant retinitis pigmentosa, pathological mechanism, overview
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-
?
additional information
?
-
-
increased activities of IMP DH and GMP synthase and in the elevated concentrations of guanylates in hepatomas and other tumor cells
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-
?
additional information
?
-
-
inhibition of the enzyme in K562 cells sensitizes the before resistant cells to methotrexate
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-
?
additional information
?
-
-
isozyme IMPDH-1 is essential for T lymphocyte development, enzyme inhibitor mycophenolic acid inhibits tumor-associated angiogenesis
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-
?
additional information
?
-
-
the enzyme is rate-limiting in the de novo synthesis of guanine nucleotides
-
-
?
additional information
?
-
-
increased activities of IMP DH and GMP synthase and in the elevated concentrations of guanylates in hepatomas and other tumor cells
-
-
?
additional information
?
-
the parasite damages fetuses in utero and threatens immunocompromized individuals
-
-
?
additional information
?
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-
the parasite damages fetuses in utero and threatens immunocompromized individuals
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-
?