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1.1.1.205: IMP dehydrogenase

This is an abbreviated version!
For detailed information about IMP dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.205

Reaction

IMP
+
NAD+
 +
H2O
=
XMP
 +
NADH
 +
H+

Synonyms

A1S_3321, BTH_I2056, class I IMPDH, class II IMPDH, dehydrogenase, inosinate, DR63_268, EC 1.2.1.14, GBAA_0008, guaB, guaB2, IMD2, IMD3, IMD4, IMP dehydrogenase, IMP DH, IMP oxidoreductase, IMP-DH, IMP:NAD oxidoreductase, IMP:NAD+ oxidoreductase, IMPD, IMPDH, IMPDH II, IMPDH-1, IMPDH-B, IMPDH-S, IMPDH1, IMPDH2, IMPDHA, IMPDHab, IMPDHba, IMPDHbt, IMPDHI, IMPDHII, IMPDHkp, IMPDHlpp, IMPDHnm, IMPDHpa, inosinate dehydrogenase, inosine 5' monophosphate dehydrogenase, inosine 5'-monophosphate dehydrogenase, inosine 5'-monophosphate dehydrogenase 2, inosine 5'-phosphate dehydrogenase, inosine 5-monophosphate dehydrogenase, inosine 5-monophosphate dehydrogenase 2, inosine 5-monophosphate dehydrogenase type I, inosine 5’ -monophosphate dehydrogenase, inosine 5’-monophosphate dehydrogenase 2, inosine monophosphate dehydrogenase, inosine monophosphate dehydrogenase-1, inosine monophosphate dehydrogenase-2, inosine monophosphate oxidoreductase, inosine-5'-monophosphate dehydrogenase, inosine-5'-phosphate dehydrogenase, inosine-5-monophosphate dehydrogenase, inosinic acid 5’-monophosphate dehydrogenase, inosinic acid dehydrogenase, lpg1723, mpaF, NMC1103, Raspberry protein, Rv3411c, SOI12, Superoxide-inducible protein 12, type 1 inosine monophosphate, type 2 inosine monophosphate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.205 IMP dehydrogenase

Cloned

Cloned on EC 1.1.1.205 - IMP dehydrogenase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
Bacillus subtilis
-
Chinese hamster
DNA and amino acid sequence determination and analysis, two splicing variants, a short and a large one, overview
DNA and amino acid sequence determination and analysis, two splicing variants, a short and a large one, overview, expression of FLAG-tagged large splicing variant in the parasite with localization in the cytoplasm
expressed in Escherichia coli
expressed in Escherichia coli BL21 cells
expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli BL21(DE3) DELTAguaB cells
expressed in Escherichia coli strain BL21 (DE3) using a pGEX-KG vector
-
expressed in Morris hepatoma 3924A cells
-
expressed in Sf9 insect cells
expression as fusion protein with green fluorescence protein, in HEK-293 cell, HeLa cell and COS cell, and expression in Escherichia coli
-
expression in Escherichia coli
expression in Eshcerichia coli
expression in HeLa cell and CHO cell
expression of full-length type I isozyme and of the His-tagged type I isozyme subdomain in Escherichia coli
-
expression of His-tagged type II IMPDH in Escherichia coli strain BL21(DE3)
-
expression of isoyzmes IMPDH I and IMPDH II in Escherichia coli strain BL21(DE3)
-
expression of the full-length enzyme and the alphabeta core domain of the enzyme in Escherichia coli
-
expression of wild-type and mutant enzyme core domains in Escherichia coli
-
expression of wild-type and mutant enzymes in enzyme-deficient Escherichia coli strain H712
-
expression of wild-type and mutant IMPDH1s in enzyme-deficient Escherichia coli strain H712 and in HeLa cells, in the latter as GFP-fusion proteins
gene A1S_3321, sequence comparisons, functional recombinant overexpression of the His-tagged soluble enzyme in Escherichia coli strain BL21(DE3)/pDIA17, the enzyme forms a turbid solution, regardless of the protein concentration or buffer composition
-
gene guaB, recombinant expresion of HIs8-tagged wild-type and mutant enzymes in Escherichia coli
gene guaB, recombinant overexpression of wild-type and mutant enzymes in Escherichia coli strain BL21(DE3)
gene guaB, sequence comparisons, functional recombinant overexpression of the His-tagged soluble enzyme in Escherichia coli strain BL21(DE3)/pDIA17
gene guaB, sequence comparisons, functional recombinant overexpression of the soluble His-tagged enzyme in Escherichia coli strain BL21(DE3)/pDIA17
Q81W29
gene guaB, sequence comparisons, recombinant expression of wild-type and mutant enzymes in Escherichia coli
gene guaB2, recombinant expression in Escherichia coli strain C41(DE3)
gene guaB2, recombinant expression of wild-type and mutant enzymes in Escherichia coli strain BL21(DE3)
gene IMH3, DNA sequence determination of wild-type and mutant IMH3, expression in enzyme-deficient Escherichia coli strain H712, subcloning in Escherichia coli strain DH5alpha
gene impdh, sequence comparisons, recombinant expression of N-terminally His-tagged long and short enzyme CBS-deletion mutants, BaIMPDHDELTAL and BaIMPDHDELTAS, in Escherichia coli
-
gene impdh, sequence comparisons, recombinant expression of N-terminally His-tagged long enzyme CBS-deletion mutant, ClpIMPDHDELTAL, in Escherichia coli
-
gene impdh, sequence comparisons, recombinant expression of N-terminally His-tagged long enzyme CBS-deletion mutant, VcIMPDHDELTAL, in Escherichia coli
-
gene impdh, sequence comparisons, recombinant expression of N-terminally His-tagged short enzyme CBS-deletion mutant, CjIMPDHDELTAS, in Escherichia coli
-
gene IMPDH2, recombinant expression in Escherichia coli strain BL21(DE3), subcloning in Escherichia coli strain DH5alpha
genes from: Leishmania donovani
-
human
isoform IMPDH2, expression in Escherichia coli
overexpression of IMPDH2 in human erythroleukemia K562 cells, expression analysis, the enzyme expression affects the cytotoxicity of methotrexate, overview
-
pET32 expression plasmid, from which the impdh gene is inducibly overexpressed in Escherichia coli BL21 (DE3) to produce IMPDH with a hexahistidyl N-terminus
-
recombinant expression of N-terminally His-tagged enzyme in Escherichia coli strain BL21(DE3)
type I and type II
-
type II
-