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Information on EC 5.1.1.17 - isopenicillin-N epimerase

for references in articles please use BRENDA:EC5.1.1.17

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IUBMB Comments

This enzyme contains pyridoxal phosphate. Epimerization at C-5 of the 5-amino-5-carboxypentanoyl group to form penicillin N is required to make a substrate for EC 1.14.20.1, deactoxycephalosporin-C synthase, to produce cephalosporins. Forms part of the penicillin biosynthesis pathway (for pathway, click here).

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

Synonyms
cefd2, isopenicillin n epimerase, isopenicillin n-coa epimerase, ipn epimerase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
isopenicillin N = penicillin N
show the reaction diagram
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