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EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 5.1.1.17biotechnology production of beta-lactam antibiotics 700004
Display the word mapDisplay the reaction diagram Show all sequences 5.1.1.17biotechnology The results indicate that Penecillium chrysogenum can be used as heterologous host for the production of deacetylcephalosporin C 673028
Display the word mapDisplay the reaction diagram Show all sequences 5.1.1.17medicine the conversion of isopenicillin N into penicillin N is part of the cephalosporin biosynthesis pathway. Cephalosporin is one of the most potent beta-lactam antibiotics, widely used in the treatment of infectious diseases 660640
Display the word mapDisplay the reaction diagram Show all sequences 5.1.1.17synthesis epimerization is a rate-limiting step in cephalosporin biosynthesis in Acremonium chrysogenum. When epimerase activity is enhanced, there is a clear increase in cephalosporin production. Thus, this method provides a strategy that could easily be applied to improve industrial cephalosporin producing strains -, 662877
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