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EC Number
Natural Substrates
Commentary (Nat. Sub.)
5.1.1.17
isopenicillin N
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5.1.1.17
isopenicillin N
part of the cephalosporin pathway
5.1.1.17
isopenicillin N
enzyme epimerizes the side chain of alpha-aminoadipic acid in isopenicillin N from the L- to the D-configuration, this is an important step since the next enzyme in the pathway, DAOCS, is unable to use isopenicillin N as substrate, in spite of the apparent minor structural difference between the two molecules
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