Reference on EC 4.2.2.8 - heparin-sulfate lyase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hovingh, P.; Linker, A.
The enzymatic degradation of heparin and heparitin sulfate. 3. Purification of a heparitinase and a heparinase from flavobacteria
J. Biol. Chem.
245
6170-6175
1970
Flavobacteriia
Manually annotated by BRENDA team
Nader, H.B.; Dietrich, C.P.; Bounassi, V.; Colburn, P.
Heparin sequences in the heparan sulfate chains of an endothelial cell proteoglycan
Proc. Natl. Acad. Sci. USA
84
3565-3569
1987
Pedobacter heparinus
Manually annotated by BRENDA team
Prinz, R.; Klein, U.; Sudhakaran, P.R.; Sinn, W.; Ullrich, K.; von Figura, K.
Metabolism of sulfated glycosaminoglycans in rat hepatocytes. Synthesis of heparan sulfate and distribution into cellular and extracellular pools
Biochim. Biophys. Acta
630
402-413
1980
Rattus norvegicus
Manually annotated by BRENDA team
Nader H.B.; Porcionatto M.A.; Tersariol, L.S.; Pinhal, M.A.S.; Oliveira, F.W.; Moraes, C.T.; Dietrich, C.P.
Purification and substrate specificity of heparitinase I and heparitinase II from Flavobacterium heparinum. Analyses of the heparin and heparan sulfate degradation products by 13C NMR spectroscopy
J. Biol. Chem.
265
16807-16813
1990
Pedobacter heparinus
Manually annotated by BRENDA team
Desai, U.R.; Wang, H.W.; Linhardt, R.J.
Specificity studies on the heparin lyases from Flavobacterium heparinum
Biochemistry
32
8140-8145
1993
Pedobacter heparinus
Manually annotated by BRENDA team
Linhardt, R.J.; Turnbull, J.E.; Wang, H.M.; Lofanathan, D.; Gallagher, J.T.
Examination of the substrate specificity of heparin and heparan sulfate lyases
Biochemistry
29
2611-2617
1990
Pedobacter heparinus
Manually annotated by BRENDA team
Yamada, S.; Sakamoto, K.; Tsuda, H.; Yoshida, K.; Sugahara, K.; Khoo, K.H.; Morris, H.R.; Dell, A.
Structural studies on the tri- and tetrasaccharides isolated from porcine intestinal heparin and characterization of heparinase/heparitinases using them as substrates
Glycobiology
4
69-78
1994
Pedobacter heparinus
Manually annotated by BRENDA team
Suhahara, K.; Tohno-oka, R.; Yamada, S.; Khoo, K.H.; Morris, H.R.; Dell, A.
Structural studies on the oligosaccharides isolated from bovine kidney heparan sulphate and characterization of bacterial heparitinases used as substrates
Glycobiology
4
535-544
1994
Pedobacter heparinus
Manually annotated by BRENDA team
Graham, L.D.; Mitchell, S.M.; Underwood, P.A.
Inhibition of platelet heparitinase by phosphorothioate DNA oligonucleotides
Biochem. Mol. Biol. Int.
37
239-246
1995
Homo sapiens
Manually annotated by BRENDA team
Brickman, M.C.; Gerhart, J.C.
Heparitinase inhibition of mesoderm induction and gastrulation in Xenopus laevis embryos
Dev. Biol.
164
484-501
1994
Pedobacter heparinus
Manually annotated by BRENDA team
Pojasek, K.; Shriver, Z.; Hu, Y.; Sasisekharan, R.
Histidine 295 and histidine 510 are crucial for the enzymatic degradation of heparan sulfate by heparinase III
Biochemistry
39
4012-4019
2000
Pedobacter heparinus
Manually annotated by BRENDA team
Chai, W.; Leteux, C.; Westling, C.; Lindahl, U.; Feizi, T.
Relative susceptibilities of the glucosamine-glucuronic acid and N-acetylglucosamine-glucuronic acid linkages to heparin lyase III
Biochemistry
43
8590-8599
2004
Pedobacter heparinus
Manually annotated by BRENDA team
Wei, Z.; Lyon, M.; Gallagher, J.T.
Distinct substrate specificities of bacterial heparinases against N-unsubstituted glucosamine residues in heparan sulfate
J. Biol. Chem.
280
15742-15748
2005
Pedobacter heparinus
Manually annotated by BRENDA team
Rops, A.L.; Jacobs, C.W.; Linssen, P.C.; Boezeman, J.B.; Lensen, J.F.; Wijnhoven, T.J.; van den Heuvel, L.P.; van Kuppevelt, T.H.; van der Vlag, J.; Berden, J.H.
Heparan sulfate on activated glomerular endothelial cells and exogenous heparinoids influence the rolling and adhesion of leucocytes
Nephrol. Dial. Transplant.
22
1070-1077
2007
Pedobacter heparinus
Manually annotated by BRENDA team
Babu, P.; Kuberan, B.
Fluorescent-tagged heparan sulfate precursor oligosaccharides to probe the enzymatic action of heparitinase I
Anal. Biochem.
396
124-132
2010
Pedobacter heparinus
Manually annotated by BRENDA team
Hyun, Y.J.; Lee, J.H.; Kim, D.H.
Cloning, overexpression, and characterization of recombinant heparinase III from Bacteroides stercoris HJ-15
Appl. Microbiol. Biotechnol.
86
879-890
2010
Bacteroides stercoris, Bacteroides stercoris (C7EXL6), Bacteroides stercoris HJ-15, Bacteroides stercoris HJ-15 (C7EXL6)
Manually annotated by BRENDA team
Raman, K.; Kuberan, B.
Differential effects of heparitinase I and heparitinase III on endothelial tube formation in vitro
Biochem. Biophys. Res. Commun.
398
191-193
2010
Pedobacter heparinus
Manually annotated by BRENDA team
Chen, S.; Ye, F.; Chen, Y.; Chen, Y.; Zhao, H.; Yatsunami, R.; Nakamura, S.; Arisaka, F.; Xing, X.H.
Biochemical analysis and kinetic modeling of the thermal inactivation of MBP-fused heparinase I: implications for a comprehensive thermostabilization strategy
Biotechnol. Bioeng.
108
1841-1851
2011
Pedobacter heparinus
Manually annotated by BRENDA team
Hashimoto, W.; Maruyama, Y.; Nakamichi, Y.; Mikami, B.; Murata, K.
Crystal structure of Pedobacter heparinus heparin lyase Hep III with the active site in a deep cleft
Biochemistry
53
777-786
2014
Pedobacter heparinus, Pedobacter heparinus (Q59289), Pedobacter heparinus DSM 2366 (Q59289)
Manually annotated by BRENDA team
Dong, W.; Lu, W.; McKeehan, W.L.; Luo, Y.; Ye, S.
Structural basis of heparan sulfate-specific degradation by heparinase III
Protein Cell
3
950-961
2012
Bacteroides thetaiotaomicron, Bacteroides thetaiotaomicron (Q89YR9), Bacteroides thetaiotaomicron DSM 2079 (Q89YR9)
Manually annotated by BRENDA team
Carnachan, S.M.; Bell, T.J.; Sims, I.M.; Smith, R.A.A.; Nurcombe, V.; Cool, S.M.; Hinkley, S.F.R.
Determining the extent of heparan sulfate depolymerisation following heparin lyase treatment
Carbohydr. Polym.
152
592-597
2016
Pedobacter heparinus
Manually annotated by BRENDA team
Hu, G.; Shao, M.; Gao, X.; Wang, F.; Liu, C.
Probing cleavage promiscuity of heparinase III towards chemoenzymatically synthetic heparan sulfate oligosaccharides
Carbohydr. Polym.
173
276-285
2017
Pedobacter heparinus, Pedobacter heparinus (Q05819)
Manually annotated by BRENDA team
Gu, Y.; Lu, M.; Wang, Z.; Wu, X.; Chen, Y.
Expanding the catalytic promiscuity of heparinase III from Pedobacter heparinus
Chemistry
23
2548-2551
2017
Pedobacter heparinus
Manually annotated by BRENDA team
Ulaganathan, T.; Shi, R.; Yao, D.; Gu, R.X.; Garron, M.L.; Cherney, M.; Tieleman, D.P.; Sterner, E.; Li, G.; Li, L.; Linhardt, R.J.; Cygler, M.
Conformational flexibility of PL12 family heparinases structure and substrate specificity of heparinase III from Bacteroides thetaiotaomicron (BT4657)
Glycobiology
27
176-187
2017
Bacteroides thetaiotaomicron, Bacteroides thetaiotaomicron (Q89YS4), Bacteroides thetaiotaomicron DSM 2079 (Q89YS4)
Manually annotated by BRENDA team
Gu, Y.; Wu, X.; Liu, H.; Pan, Q.; Chen, Y.
Photoswitchable heparinase III for enzymatic preparation of low molecular weight heparin
Org. Lett.
20
48-51
2018
Pedobacter heparinus (Q59289)
Manually annotated by BRENDA team