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EC 3.2.2.22 Details
EC number
3.2.2.22
Accepted name
rRNA N-glycosylase
Reaction
Hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes
Other name(s)
ribosomal ribonucleate N-glycosidase,
nigrin b,
RNA N-glycosidase,
rRNA N-glycosidase,
ricin,
momorcochin-S,
Mirabilis antiviral protein,
momorcochin-S,
gelonin,
saporins
Systematic name
rRNA N-glycohydrolase
CAS registry number
113756-12-0
Comment
Ricin A-chain and related toxins show this activity. Naked rRNA is attacked more slowly than rRNA in intact ribosomes. Naked rRNA from Escherichia coli is cleaved at a corresponding position.
History
created 1990, modified 2000
EC Tree
3.2.2.18 created 1984, deleted 1989