EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.24.56 | Alzheimer Disease |
12809979 |
Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: evidence of effect modification by apolipoprotein E (APOE). |
causal interaction
diagnostic usage
unassigned |
2
1
0 |
| 3.4.24.56 | Alzheimer Disease |
12850277 |
Non-covalent interaction of ubiquitin with insulin-degrading enzyme. |
causal interaction
unassigned |
3
0 |
| 3.4.24.56 | Alzheimer Disease |
14755451 |
No association between the insulin degrading enzyme gene and Alzheimer's disease in a Japanese population. |
causal interaction
ongoing research
unassigned |
1
2
0 |
| 3.4.24.56 | Alzheimer Disease |
15088150 |
Sequence variation in the proximity of IDE may impact age at onset of both Parkinson disease and Alzheimer disease. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 3.4.24.56 | Alzheimer Disease |
15181249 |
Insulin-degrading enzyme, apolipoprotein E, and Alzheimer's disease. |
causal interaction
unassigned |
3
0 |
| 3.4.24.56 | Alzheimer Disease |
15277615 |
Insulin-degrading enzyme and Alzheimer disease: a genetic association study in the Han Chinese. |
causal interaction
unassigned |
1
0 |
| 3.4.24.56 | Alzheimer Disease |
15590928 |
Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimer's disease intervention. |
therapeutic application
unassigned |
3
0 |
| 3.4.24.56 | Alzheimer Disease |
15718037 |
Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain. |
causal interaction
unassigned |
3
0 |
| 3.4.24.56 | Alzheimer Disease |
15800373 |
Insulysin: an allosteric enzyme as a target for Alzheimer's disease. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 3.4.24.56 | Alzheimer Disease |
15858813 |
Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme. |
causal interaction
diagnostic usage
unassigned |
1
2
0 |
