EC Number |
Application |
Reference |
---|
3.6.4.10 | analysis |
high-throughput screening method in 96-well plates for ATPase activity of DnaK. Screening of potential inhibitors |
684406 |
3.6.4.10 | drug development |
Hsp70 proteins are targets for the drug-based treatments for cancers, misfolding diseases, and protein folding disorders |
735005 |
3.6.4.10 | drug development |
human heat shock protein 90 is a target in cancer drug discovery, inhibition of ATP hydrolysis is a validated avenue for the development of anticancer therapies |
734536 |
3.6.4.10 | drug development |
reconstitution of the entire Plasmodium translocon of exported proteins, PTEX, to aid structure-based design of anti-malarial drugs |
735222 |
3.6.4.10 | medicine |
development of a potent cytostatic anti-tumor and immunosuppressive agent, 15-deoxyspergualin, a synthetic analogue of the antibiotic spergualin, to prevent rejection in kidney transplant recipients |
210516 |
3.6.4.10 | medicine |
Hsp90 is a molecular target for cancer therapy |
667113 |
3.6.4.10 | medicine |
Hsp90 is a target for cancer therapy |
719075 |