EC Number |
Recommended Name |
Localization |
GeneOntology No. |
Reference |
---|
3.4.23.5 | cathepsin D |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
36919, 36935, 36952, 36953, 36958, 679068, 695420, 696009, 696295, 696402, 697479, 697723, 698022, 699114, 700090, 700128, 711326, 711354, 711855, 711892, 712050, 712160, 713125, 717517, 717631, 718306, 731091, 731168, 731411, 731454, 731700, 731831, 731928, 732059, 752655, 753609, 753730, 754306, 754432, 754635, 755429, 755464, 755627 |
3.4.23.5 | cathepsin D |
lysosome |
the mature form of cathepsin D is located at lysosome |
GO:0005764 AmiGO QuickGO |
713109 |
3.4.23.B1 | napsin |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
657686 |
3.4.23.B14 | plasmepsin IV |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
707051 |
3.4.24.71 | endothelin-converting enzyme 1 |
lysosome |
isozyme ECE-1b |
GO:0005764 AmiGO QuickGO |
683437 |
3.5.1.23 | ceramidase |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
171991, 668638, 696396, 700316, 719536, 733395, 734696, 752968, 753491, 753570, 754849, 754939, 754949 |
3.5.1.23 | ceramidase |
lysosome |
acid ceramidase |
GO:0005764 AmiGO QuickGO |
711799, 719197 |
3.5.1.23 | ceramidase |
lysosome |
CDase is distributed with late endosomes/lysosomes in hepatocytes |
GO:0005764 AmiGO QuickGO |
656010 |
3.5.1.23 | ceramidase |
lysosome |
of hepatocytes |
GO:0005764 AmiGO QuickGO |
733408 |
3.5.1.23 | ceramidase |
lysosome |
predominantly |
GO:0005764 AmiGO QuickGO |
711949 |
3.5.1.26 | N4-(beta-N-acetylglucosaminyl)-L-asparaginase |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
209047, 209048, 209051, 209052, 209055, 209061, 209066, 668879, 681417, 712162, 712919, 735290, 753573, 753910, 755339 |
3.5.1.26 | N4-(beta-N-acetylglucosaminyl)-L-asparaginase |
lysosome |
enzymic catalysis takes place in lysosomes |
GO:0005764 AmiGO QuickGO |
654537 |
3.5.1.26 | N4-(beta-N-acetylglucosaminyl)-L-asparaginase |
lysosome |
in the lysosomes, the C-termini of both alpha- and beta-subunits are trimmed by proteases, resulting in the mature form of AGA, though these trimming steps are not necessary for the catalytic activity of AGA |
GO:0005764 AmiGO QuickGO |
753910 |
3.5.1.4 | amidase |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
686040 |
3.5.1.52 | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
288909 |
3.5.1.60 | N-(long-chain-acyl)ethanolamine deacylase |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
-, 735061, 752354, 752355, 752811, 752960, 753248, 753491, 754356, 754610, 754903, 755270 |
3.5.1.60 | N-(long-chain-acyl)ethanolamine deacylase |
lysosome |
the enzyme is believed to be transported by the mannose-6-phosphate pathway to the acidic late endosomes and/or lysosomes |
GO:0005764 AmiGO QuickGO |
734562 |
3.5.1.75 | urethanase |
lysosome |
highest activity, located mainly in the lysosomal fraction |
GO:0005764 AmiGO QuickGO |
209238 |
3.6.1.18 | FAD diphosphatase |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
209915 |
3.6.1.18 | FAD diphosphatase |
lysosome |
membrane |
GO:0005764 AmiGO QuickGO |
209923 |
3.6.1.2 | trimetaphosphatase |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
209932, 209935, 209941, 667198 |
3.6.1.2 | trimetaphosphatase |
lysosome |
basal elongated lysosome |
GO:0005764 AmiGO QuickGO |
209935 |
3.6.1.2 | trimetaphosphatase |
lysosome |
round and tubular structures |
GO:0005764 AmiGO QuickGO |
209940 |
3.6.1.26 | CDP-diacylglycerol diphosphatase |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
210005 |
3.6.1.43 | dolichyldiphosphatase |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
289076 |
3.6.2.1 | adenylylsulfatase |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
289087, 289089, 289090 |
4.2.2.7 | heparin lyase |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
5975 |
4.6.1.14 | glycosylphosphatidylinositol diacylglycerol-lyase |
lysosome |
predominantly acidic enzyme form |
GO:0005764 AmiGO QuickGO |
648768 |
4.6.1.18 | pancreatic ribonuclease |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
134535 |
4.6.1.19 | ribonuclease T2 |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
656707 |
5.6.1.3 | plus-end-directed kinesin ATPase |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
210552 |
6.1.1.4 | leucine-tRNA ligase |
lysosome |
co-localization of LRS and lysosome-associated membrane glycoprotein 2, LAMP2 |
GO:0005764 AmiGO QuickGO |
744247 |
6.3.5.5 | carbamoyl-phosphate synthase (glutamine-hydrolysing) |
lysosome |
coexpression of small GTPase Rheb with CAD leads to increased accumulation of CAD on lysosomes |
GO:0005764 AmiGO QuickGO |
745319 |
7.1.2.1 | P-type H+-exporting transporter |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
712552, 713383 |
7.1.2.2 | H+-transporting two-sector ATPase |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
712552, 713383 |
7.2.1.3 | ascorbate ferrireductase (transmembrane) |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
389971, 673552 |
7.2.1.3 | ascorbate ferrireductase (transmembrane) |
lysosome |
LCytb |
GO:0005764 AmiGO QuickGO |
744757 |
7.2.2.12 | P-type Zn2+ transporter |
lysosome |
isoform ZntB is the main Zn2+ transporter of the lysosome |
GO:0005764 AmiGO QuickGO |
751181 |
7.2.2.8 | P-type Cu+ transporter |
lysosome |
high Cu2+ concentration redistributes ATP7B to late endosomes or lysosomes that move along the axon in live hippocampal neurons |
GO:0005764 AmiGO QuickGO |
734662 |
7.4.2.5 | bacterial ABC-type protein transporter |
lysosome |
- |
GO:0005764 AmiGO QuickGO |
670487, 687663, 710640, 734330 |