EC Number   |
Activating Compound |
Reference |
|---|
   3.1.1.47 | dithiothreitol |
1.3fold increase in activity, isozyme II from cerebrospinal fluid |
649522 |
| 3.1.1.47 | more |
3fold increase in activity in subjects with meningitis |
649522 |
| 3.1.1.47 | deoxycholate |
activation |
80945 |
| 3.1.1.47 | more |
dose-dependent induction of enzyme expression by pioglitazone |
667771 |
| 3.1.1.47 | lipopolysaccharides |
induce plasma enzyme expression in several tissues, overview, induction is 50% inhibited by administration of antagonists BN 50739 and WEB 2170 |
652009 |
| 3.1.1.47 | dyslipidemia |
induces an increase in total plasma enzyme activity and alters the enzyme distribution between proatherogenic apoB- and antiatherogenic apo L-containing lipoproteins by increasing the enzyme activity associated with apoB-containing lipoproteins, atorvastin and fenofibrate can restore the normal level by reduction of LDL amount |
649802 |
| 3.1.1.47 | more |
membrane binding of HpPAF-AH increases the activity of enzyme, by interfacial activation. The lipid composition of membrane vesicles, by changing the physicochemical properties, differentially modulates the binding, partial membrane penetration and the activity of the enzyme, detailed overview |
714337 |
| 3.1.1.47 | platelet-activating factor |
regulatory function on the enzyme form from hepatocytes |
650326 |
| 3.1.1.47 | platelet-activating factor |
regulatory function on the enzyme form from HepG2 cells and monocyte-derived macrophages, no effect on erythrocytes and erythrocyte isozyme |
650326 |
| 3.1.1.47 | corticoids |
regulatory function on the enzyme form from HL-60 cells |
650326 |
