2.3.1.296: omega-hydroxyceramide transacylase
This is an abbreviated version!
For detailed information about omega-hydroxyceramide transacylase, go to the full flat file.
Word Map on EC 2.3.1.296
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2.3.1.296
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ichthyosis
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alox12b
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abca12
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cyp4f22
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aloxe3
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nipal4
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cornification
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erythroderma
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stratum
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scaling
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sdr9c7
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lamellar
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ichthyosiform
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corneum
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acylceramide
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harlequin
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genodermatoses
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collodion
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pnplas
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cornified
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corneocytes
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scaly
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non-syndromic
- 2.3.1.296
- ichthyosis
- alox12b
-
abca12
- cyp4f22
- aloxe3
-
nipal4
-
cornification
- erythroderma
-
stratum
-
scaling
-
sdr9c7
-
lamellar
-
ichthyosiform
- corneum
- acylceramide
- harlequin
-
genodermatoses
-
collodion
-
pnplas
-
cornified
-
corneocytes
-
scaly
-
non-syndromic
Reaction
Synonyms
omega-hydroxyceramide transacylase, patatin-like phospholipase domain-containing 1, patatin-like phospholipase domain-containing lipase 1, PNPLA1
ECTree
2.3.1.296 omega-hydroxyceramide transacylaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 2.3.1.296 - omega-hydroxyceramide transacylase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
a linoleate-containing triacyl-sn-glycerol + an ultra-long-chain omega-hydroxyceramide
a diacyl-sn-glycerol + a linoleate-esterified acylceramide
linoleate-containing triacyl-sn-glycerol + N-omega-hydroxytriacontanoyl-D-erythro-sphingosine
?
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-
-
-
?
a linoleate-containing triacyl-sn-glycerol + an ultra-long-chain omega-hydroxyceramide
a diacyl-sn-glycerol + a linoleate-esterified acylceramide
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-
-
-
?
a linoleate-containing triacyl-sn-glycerol + an ultra-long-chain omega-hydroxyceramide
a diacyl-sn-glycerol + a linoleate-esterified acylceramide
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-
-
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ir
a linoleate-containing triacyl-sn-glycerol + an ultra-long-chain omega-hydroxyceramide
a diacyl-sn-glycerol + a linoleate-esterified acylceramide
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-
-
?
a linoleate-containing triacyl-sn-glycerol + an ultra-long-chain omega-hydroxyceramide
a diacyl-sn-glycerol + a linoleate-esterified acylceramide
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-
-
-
?
a linoleate-containing triacyl-sn-glycerol + an ultra-long-chain omega-hydroxyceramide
a diacyl-sn-glycerol + a linoleate-esterified acylceramide
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-
-
-
ir
a linoleate-containing triacyl-sn-glycerol + an ultra-long-chain omega-hydroxyceramide
a diacyl-sn-glycerol + a linoleate-esterified acylceramide
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the enzyme is highly linoleate-selective
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-
?
additional information
?
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ABHD5 is a coactivator of the enzyme that stimulates the esterification of omega-hydroxy ceramides with linoleic acid for omega-O-acylceramide biosynthesis
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-
?
additional information
?
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ABHD5 promotes enzyme-dependent acylceramide production by retaining triglycerides in the endoplasmic reticulum and presenting them to the enzyme to promote substrate recognition
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-
?
additional information
?
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the enzyme fails to catalyze the hydrolysis of triglyceride as a lipase
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-
?
additional information
?
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-
ABHD5 is a coactivator of the enzyme that stimulates the esterification of omega-hydroxy ceramides with linoleic acid for omega-O-acylceramide biosynthesis
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-
?
