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2.1.1.361: [histone H4]-lysine20 N-methyltransferase

This is an abbreviated version!
For detailed information about [histone H4]-lysine20 N-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.361

Reaction

S-adenosyl-L-methionine
+
a [histone H4]-L-lysine20
=
S-adenosyl-L-homocysteine
 +
a [histone H4]-N6-methyl-L-lysine20

Synonyms

CG3307, EC 2.1.1.43, H4-K20-specific HMT, H4-K20-specific HMTase, H4-K20-specific methyltransferase, H4K20 di- and trimethyltransferase, H4K20 methyltransferase, H4K20 protein lysine methyltransferase, histone 4 K20 methyltransferase, histone H4 Lys 20 methyltransferase, histone H4 Lys 20 monomethyltransferase, histone H4 lysine 20 methyltransferase, histone H4 lysine 20 monomethyltransferase, histone H4 lysine20 trimethyltransferase, histone H4-K20 methyltransferase, histone H4-K20 trimethyltransferase, histone H4-lysine 20-specific methyltransferase, histone lysine methyltransferase, Hmt4-20, KMT5a, PKMT, Pr-Set7, PR-Set7/9, protein lysine methyltransferase, SET-4, SET8, SETD8, Suv4-20, Suv4-20h2

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.361 [histone H4]-lysine20 N-methyltransferase

Posttranslational Modification

Posttranslational Modification on EC 2.1.1.361 - [histone H4]-lysine20 N-methyltransferase

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POSTTRANSLATIONAL MODIFICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phosphoprotein
the enzyme is phosphorylated at Ser 29 specifically by the cyclin-dependent kinase 1/cyclinB complex. This event results in the removal of the enzyme from mitotic chromosomes and prevents enzyme degradation but does not affect the enzyme's methyltransferase activity