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1.14.14.116: averantin hydroxylase

This is an abbreviated version!
For detailed information about averantin hydroxylase, go to the full flat file.

Reaction

(1'S)-averantin
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(1'S,5'R)-5'-hydroxyaverantin
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

AdhA, AVN hydroxylase, AVN monooxygenase, avnA, CYP60A1, EC 1.14.13.174

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.116 averantin hydroxylase

Systematic Name

Systematic Name on EC 1.14.14.116 - averantin hydroxylase

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SYSTEMATIC NAME
IUBMB Comments
(1'S)-averantin,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (5'-hydroxylating)
A cytochrome P-450 (heme-thiolate) protein isolated from the saprophytic mold Aspergillus parasiticus. Involved in aflatoxin biosynthesis. Does not react with (1'R)-averantin.