1.14.14.116: averantin hydroxylase
This is an abbreviated version!
For detailed information about averantin hydroxylase, go to the full flat file.
Reaction
Synonyms
AdhA, AVN hydroxylase, AVN monooxygenase, avnA, CYP60A1, EC 1.14.13.174
ECTree
1.14.14.116 averantin hydroxylaseAdvanced search results
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Substrates Products on EC 1.14.14.116 - averantin hydroxylase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'R)-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
averantin + [reduced NADPH-hemoprotein reductase] + O2
5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
(1'S)-averantin + NADPH + H+ + O2
(1'S,5'R)-5'-hydroxyaverantin + NADP+ + H2O
-
-
-
-
?
(1'S)-averantin + NADPH + H+ + O2
(1'S,5'R)-5'-hydroxyaverantin + NADP+ + H2O
-
-
-
-
?
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'R)-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway. It specifically hydroxylates (1'S)-averantin to the diastereomers (1'S,5'R)-hydroxyaverantin and (1'S,5'S)-hydroxyaverantin
-
-
?
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'R)-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
-
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway. No activity with (1'R)-averantin. The enzyme specifically hydroxylates (1'S)-averantin to both diastereomers (1'S,5'R)-hydroxyaverantin and (1'S,5'S)-hydroxyaverantin
-
-
?
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'R)-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
-
no activity with (1'R)-averantin. The enzyme specifically hydroxylates (1'S)-averantin to both diastereomers (1'S,5'R)-hydroxyaverantin and (1'S,5'S)-hydroxyaverantin
-
-
?
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'R)-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
the enzyme specifically hydroxylates (1'S)-averantin to the diastereomers (1'S,5'R)-hydroxyaverantin and (1'S,5'S)-hydroxyaverantin
-
-
?
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'R)-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway. It specifically hydroxylates (1'S)-averantin to the diastereomers (1'S,5'R)-hydroxyaverantin and (1'S,5'S)-hydroxyaverantin
-
-
?
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'R)-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
the enzyme specifically hydroxylates (1'S)-averantin to the diastereomers (1'S,5'R)-hydroxyaverantin and (1'S,5'S)-hydroxyaverantin
-
-
?
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway. It specifically hydroxylates (1'S)-averantin to the diastereomers (1'S,5'R)-hydroxyaverantin and (1'S,5'S)-hydroxyaverantin
-
-
?
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
-
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway. No activity with (1'R)-averantin. The enzyme specifically hydroxylates (1'S)-averantin to both diastereomers (1'S,5'R)-hydroxyaverantin and (1'S,5'S)-hydroxyaverantin
-
-
?
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
-
no activity with (1'R)-averantin. The enzyme specifically hydroxylates (1'S)-averantin to both diastereomers (1'S,5'R)-hydroxyaverantin and (1'S,5'S)-hydroxyaverantin
-
-
?
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
the enzyme specifically hydroxylates (1'S)-averantin to the diastereomers (1'S,5'R)-hydroxyaverantin and (1'S,5'S)-hydroxyaverantin
-
-
?
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway. It specifically hydroxylates (1'S)-averantin to the diastereomers (1'S,5'R)-hydroxyaverantin and (1'S,5'S)-hydroxyaverantin
-
-
?
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2
(1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
the enzyme specifically hydroxylates (1'S)-averantin to the diastereomers (1'S,5'R)-hydroxyaverantin and (1'S,5'S)-hydroxyaverantin
-
-
?
averantin + [reduced NADPH-hemoprotein reductase] + O2
5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
averantin + [reduced NADPH-hemoprotein reductase] + O2
5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
additional information
?
-
-
the enzyme does not act on (1'R)-averantin
-
-
?
additional information
?
-
-
the enzyme does not act on (1'R)-averantin
-
-
?
