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Information on EC 1.14.14.116 - averantin hydroxylase

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EC Tree
IUBMB Comments
A cytochrome P-450 (heme-thiolate) protein isolated from the saprophytic mold Aspergillus parasiticus. Involved in aflatoxin biosynthesis. Does not react with (1'R)-averantin.
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The enzyme appears in viruses and cellular organisms
Synonyms
AdhA, AVN hydroxylase, AVN monooxygenase, avnA, CYP60A1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2 = (1'S,5'R)-5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
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(2)
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(1'S)-averantin + [reduced NADPH-hemoprotein reductase] + O2 = (1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
(1)
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