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EC Number
Protein Variants
Commentary
Reference
4.3.2.1
E296Q
retains only 0.001% residual activity
34447
4.3.2.1
N116L
no activity
34447
4.3.2.1
R115N
no activity
34447
4.3.2.1
S283A
no activity
34447
4.3.2.1
S384A
catalytic efficiency is decreased by an order of magnitude in comparison to wild-type delta II crystallin
34447
4.3.2.1
T161V
no activity
34447
4.3.2.1
Y323F
catalytic efficiency is decreased by an order of magnitude in comparison to wild-type delta II crystallin
34447
4.3.2.1
Y323I
no activity
34447
4.3.2.1
Q286R
frequently complementing allele, 2% of wild-type kcat
650042
4.3.2.1
R12Q
6% of wild-type kcat
650042
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