EC Number |
Protein Variants |
Reference |
---|
2.3.3.9 | C438S |
residue in the acetyl-CoA binding pocket |
706621 |
2.3.3.9 | C617S |
88.1% of wild-type activity |
660456 |
2.3.3.9 | C617S |
residue in the acetyl-CoA binding pocket |
706621 |
2.3.3.9 | C619S |
the mutant exhibits kinetics comparable to those of the wild type enzyme |
-, 718909 |
2.3.3.9 | D453A |
0.06% of wild-type activity |
-, 657618 |
2.3.3.9 | D475N |
the glyoxylate cycle enzyme mutant completely loses malate synthase activity but retains isocitrate lyase activity |
715749 |
2.3.3.9 | D631N |
no activity |
705567 |
2.3.3.9 | D631N |
no enzymic activity |
660456 |
2.3.3.9 | more |
enzyme disruption mutant, in absence of any supplied carbon source, spores are unable to germinate and therefore non-pathogenic. Germination and pathogenicity can be restored by addition of glucose or sucrose. In mutants, lipid mobilization and peroxisomal beta-oxidation is delayed or inhibited |
659963 |
2.3.3.9 | more |
the C-terminal domain of the glyoxylate cycle enzyme, when expressed alone (GCE(566-1165)), does not show any enzyme activity |
715749 |