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Literature summary for 2.3.3.9 extracted from
- Major roles of isocitrate lyase and malate synthase in bacterial and fungal pathogenesis (2009), Microbiology, 155, 3166-3175.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| D631N | no activity | Escherichia coli |
| R338K | 6% of wild-type activity | Escherichia coli |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Escherichia coli |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 65000 | - |
x * 65000 | Escherichia coli |
| 80000 | - |
1 * 80000 | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bradyrhizobium japonicum | - |
- |
- |
| Candida albicans | - |
- |
- |
| Escherichia coli | - |
- |
- |
| Mycobacterium tuberculosis | - |
- |
- |
| Paracoccidioides brasiliensis | - |
- |
- |
| Parastagonospora nodorum | - |
- |
- |
| Rhizobium leguminosarum | - |
- |
- |
| Rhodococcus fascians | - |
- |
- |
| Sinorhizobium meliloti | - |
- |
- |
| Xanthomonas campestris | - |
- |
- |
| Yersinia enterocolitica | - |
- |
- |
| Yersinia pestis | - |
- |
- |
| Yersinia pseudotuberculosis | - |
- |
- |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 80000 | Escherichia coli |
| multimer | x * 65000 | Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| malate synthase | - |
Sinorhizobium meliloti |
| malate synthase | - |
Bradyrhizobium japonicum |
| malate synthase | - |
Mycobacterium tuberculosis |
| malate synthase | - |
Candida albicans |
| malate synthase | - |
Yersinia pseudotuberculosis |
| malate synthase | - |
Yersinia pestis |
| malate synthase | - |
Xanthomonas campestris |
| malate synthase | - |
Rhizobium leguminosarum |
| malate synthase | - |
Yersinia enterocolitica |
| malate synthase | - |
Paracoccidioides brasiliensis |
| malate synthase | - |
Rhodococcus fascians |
| malate synthase | - |
Parastagonospora nodorum |
| malate synthase A | - |
Escherichia coli |
| malate synthase G | - |
Escherichia coli |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Parastagonospora nodorum | decrease in transcription after germination, increase of activity after germination | down |
| Yersinia pseudotuberculosis | during growth on acetate | up |
| Yersinia enterocolitica | during growth on acetate | up |
| Xanthomonas campestris | during infection of tomato plants | up |
| Candida albicans | in the presence of macrophages | up |
| Paracoccidioides brasiliensis | in the presence of macrophages | up |
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