EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
6.3.4.2 | 0.072 |
- |
1,3-dimethyluric acid |
pH 8.0, NH3-dependent CTP formation |
702613 |
6.3.4.2 | 0.072 |
- |
CTP |
mutant S568A, pH 8.1, 37°C |
715549 |
6.3.4.2 | 0.079 |
- |
1,3,7,9-tetramethyluric |
pH 8.0, Gln-dependent CTP formation |
702613 |
6.3.4.2 | 0.08 |
- |
8-oxoguanosine |
- |
674909 |
6.3.4.2 | 0.08 |
- |
8-oxoguanosine |
IC50 for inhibition of Gln-dependent CTP formation |
674909 |
6.3.4.2 | 0.087 |
- |
uric acid |
pH 8.0, NH3-dependent CTP formation |
702613 |
6.3.4.2 | 0.088 |
- |
1,3-dimethyluric acid |
pH 8.0, Gln-dependent CTP formation |
702613 |
6.3.4.2 | 0.09 |
- |
3,7-dimethyluric acid |
pH 8.0, NH3-dependent CTP formation |
702613 |
6.3.4.2 | 0.096 |
- |
1-methyluric acid |
pH 8.0, NH3-dependent CTP formation |
702613 |
6.3.4.2 | 0.1 |
- |
uric acid |
in HEPES buffer (70 mM, pH 7.3), at 37°C |
727139 |