EC Number   |
Cofactor |
Reference  |
|---|
    1.1.1.27 | NADPH |
coenzyme |
286441, 286448, 286468 |
| 1.1.1.27 | FMN |
contains non-covalently bound FMN as prosthetic group |
286450 |
| 1.1.1.27 | NAD+ |
coenzyme |
286431, 286435, 286436, 286437, 286438, 286439, 286440, 286443, 286445, 286446, 286447, 286448, 286450, 286453, 286454, 286459, 286460, 286461 |
| 1.1.1.27 | 3-acetylpyridine adenine dinucleotide |
wild-type and S163 L mutant protein bind 3-acetylpyridine adenine dinucleotide more tightly than they bind NADH |
286458 |
| 1.1.1.27 | NADH |
coenzyme |
286430, 286431, 286432, 286433, 286434, 286435, 286436, 286437, 286438, 286439, 286440, 286441, 286442, 286443, 286444, 286445, 286446, 286447, 286448, 286449, 286451, 286452, 286453, 286454, 286456, 286457, 286458, 286459, 286460, 286461, 286462, 286463, 286464, 286465, 286468, 286469, 286470, 286471 |
| 1.1.1.27 | 3-acetylpyridine adenine dinucleotide |
alternative coenzyme |
286471 |
| 1.1.1.27 | nicotinamide hypoxanthine dinucleotide |
alternative coenzyme |
286471 |
| 1.1.1.27 | thio-NAD+ |
alternative coenzyme |
286471 |
| 1.1.1.27 | 3-acetylpyridine adenine dinucleotide |
assay is based on reduction of 3-acetyl pyridine adenine dinucleotide that is specific for PfLDH, which allows the distinction of PfLDH from that of the host erythrocyte |
668525 |
| 1.1.1.27 | NAD+ |
wild-type enzyme is specific for NAD+. Mutant enzyme F16Q/I37K/D38SC81S/N85R utilizes NADP+ better than wild-type enzyme, prefers NADP+ to NAD+. Mutant F16Q/C81S/N85R utilizes NAD+ better than wild-type enzyme, weakly active wth NADP+ |
670748 |
