EC Number   |
Cofactor |
Reference |
|---|
    1.2.1.13 | NAD+ |
the highest activity is almost equal for NADP+ and NAD+, whereas the affinity for NADP+ is higher than that for NAD+ |
725013 |
| 1.2.1.13 | NAD+ |
Vmax/Km for NADP+ is 33fold higher compared to Vmax/Km for NAD+ |
719395 |
| 1.2.1.13 | NADH |
- |
655492, 671164, 675500, 724306 |
| 1.2.1.13 | NADH |
greater specificity for NADPH than for NADH |
655452 |
| 1.2.1.13 | NADH |
the residues Thr33 and Ser188 are involved in NADPH over NADH selectivity |
656539 |
| 1.2.1.13 | NADP+ |
- |
654627, 656414, 685291, 685362, 688696, 689485, 712646, 721392, 726000, 743027, 761625, 763095 |
| 1.2.1.13 | NADP+ |
activity is specific for NADP+ as an electron acceptor |
727725 |
| 1.2.1.13 | NADP+ |
cofactor |
11537, 11539, 287923, 287973, 287989, 287990, 287991, 287992, 287993, 287994, 287995, 287996, 287997, 287999, 288000, 288001, 288002, 288003, 288004, 288005, 288006, 288007, 288008, 288009, 288010, 288011, 288012, 288013, 288014, 288015, 288016, 288017, 288018, 288019, 288020, 288021, 288022, 288023, 288024, 288025, 288027, 288028, 288029, 288030, 288031, 288032, 288034, 288035, 288036 |
| 1.2.1.13 | NADP+ |
isoform GapB shows slight activity with NADP+. The activity is about 7-8 times less than NAD+-dependent GAPDH activity of isoform GapA |
724415 |
| 1.2.1.13 | NADP+ |
NADP+ and NAD+ react with the enzyme at the same catalytic site |
288027 |
