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Results 1 - 10 of 11 > >>
EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
23S rRNA uridine2457
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23S rRNA pseudouridine2457
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?
23S rRNA uridine2457
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23S rRNA pseudouridine2457
-
?
23S rRNA uridine2457
Escherichia coli pseudouridine synthase RluE targeting a single uridine in helix 89 (H89) in the peptidyltransferase center (PTC) of 23S rRNA. The target of RluE in H89 is Psi2457, analysis, overview
23S rRNA pseudouridine2457
-
?
23S rRNA uridine2457
Escherichia coli pseudouridine synthase RluE targeting a single uridine in helix 89 (H89) in the peptidyltransferase center (PTC) of 23S rRNA. The target of RluE in H89 is Psi2457, analysis, overview
23S rRNA pseudouridine2457
-
?
23S rRNA uridine2457
pseudouridine synthase RluE modifies U2457 in a stem of 23S RNA in Escherichia coli. This modification is located in the peptidyl transferase center of the ribosome. The stem alone is not a good RluE substrate, suggesting RluE undergoes additional interactions with other regions in the ribosome
23S rRNA pseudouridine2457
-
?
23S rRNA uridine2457
pseudouridine synthase RluE modifies U2457 in a stem of 23S RNA in Escherichia coli. This modification is located in the peptidyl transferase center of the ribosome.The stem alone is not a good RluE substrate, suggesting RluE undergoes additional interactions with other regions in the ribosome
23S rRNA pseudouridine2457
-
?
more
RluE acts as a stand-alone, highly specific enzyme forming the universally conserved pseudouridine at position 2457, located in helix 89 (H89) of the 23S rRNA in the peptidyltransferase center, detailed structure-function analysis to determine the structural elements both in RluE and in 23S rRNA required for RNA-protein interaction and pseudouridine formation
?
-
?
more
RluE acts as a stand-alone, highly specific enzyme forming the universally conserved pseudouridine at position 2457, located in helix 89 (H89) of the 23S rRNA in the peptidyltransferase center, detailed structure-function analysis to determine the structural elements both in RluE and in 23S rRNA required for RNA-protein interaction and pseudouridine formation
?
-
?
more
RluE recognizes a large part of 23S rRNA comprising both H89 and the single-stranded flanking regions which explains the high substrate specificity of RluE. Within RluE, the target RNA is recognized through sequence-specific contacts with loop L7-8 as well as interactions with loop L1-2 and the flexible N-terminal region
?
-
?
more
RluE recognizes a large part of 23S rRNA comprising both H89 and the single-stranded flanking regions which explains the high substrate specificity of RluE. Within RluE, the target RNA is recognized through sequence-specific contacts with loop L7-8 as well as interactions with loop L1-2 and the flexible N-terminal region
?
-
?
Results 1 - 10 of 11 > >>