EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.1.1.31 | more |
no activity with (R)-methyl-3-hydroxy-2-methylpropionate, glycerate, serine, beta-hydroxypyruvate, threonine, 2-hydroxybutyrate, malate, glycolate, beta-hydroxybutyrate, lactate, and 6-phosphogluconate. NADP+ is not a suitable cofactor. Also, FAD, oxidized cytochrome c, as well as the artificial electron acceptors phenazine methosulfate and dichlorophenol indophenol cannot be reduced by the enzyme |
Arabidopsis thaliana |
? |
- |
- |
1.1.1.31 | more |
no activity with D-serine, (S)-3-hydroxyisobutyrate methyl ester, (R)-3-hydroxyisobutyrate methyl ester, L-threonine and D-threonine |
Mycobacterium tuberculosis |
? |
- |
- |
1.1.1.31 | more |
no activity with D-serine, (S)-3-hydroxyisobutyrate methyl ester, (R)-3-hydroxyisobutyrate methyl ester, L-threonine and D-threonine |
Mycobacterium tuberculosis H37Rv |
? |
- |
- |
1.1.1.31 | (R)-3-hydroxyisobutyrate + NAD+ |
2% activity compared to (S)-3-hydroxyisobutyrate |
Arabidopsis thaliana |
2-methyl-3-oxopropanoate + NADH + H+ |
- |
? |
1.1.1.31 | (R)-3-hydroxyisobutyrate + NAD+ |
substrate with much less efficiency compared to (S)-3-hydroxyisobutyrate |
Mycobacterium tuberculosis |
2-methyl-3-oxopropanoate + NADH + H+ |
- |
? |
1.1.1.31 | (R)-3-hydroxyisobutyrate + NAD+ |
substrate with much less efficiency compared to (S)-3-hydroxyisobutyrate |
Mycobacterium tuberculosis H37Rv |
2-methyl-3-oxopropanoate + NADH + H+ |
- |
? |
1.1.1.31 | (S)-3-hydroxyisobutyrate + NAD+ |
- |
Arabidopsis thaliana |
2-methyl-3-oxopropanoate + NADH + H+ |
- |
? |
1.1.1.31 | (S)-3-hydroxyisobutyrate + NAD+ |
the enzyme is very specific to (S)-3-hydroxyisobutyrate |
Bacillus cereus |
2-methyl-3-oxopropanoate + NADH + H+ |
- |
? |
1.1.1.31 | (S)-3-hydroxyisobutyrate + NAD+ |
the enzyme is very specific to (S)-3-hydroxyisobutyrate |
Pseudomonas denitrificans (nom. rej.) |
2-methyl-3-oxopropanoate + NADH + H+ |
- |
? |
1.1.1.31 | (S)-3-hydroxyisobutyrate + NAD+ |
the enzyme is specific to (S)-3-hydroxyisobutyrate and prefers NAD+ as cofactor |
Mycobacterium tuberculosis |
2-methyl-3-oxopropanoate + NADH + H+ |
- |
? |