EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
    1.1.1.31 | L-3-hydroxyisobutyrate + NAD+ |
- |
Aciculoconidium aculeatum |
L-2-methyl-3-oxopropionate + NADH |
- |
? |
| 1.1.1.31 | (R)-3-hydroxyisobutyrate + NAD+ |
2% activity compared to (S)-3-hydroxyisobutyrate |
Arabidopsis thaliana |
2-methyl-3-oxopropanoate + NADH + H+ |
- |
? |
| 1.1.1.31 | (S)-3-hydroxyisobutyrate + NAD+ |
- |
Arabidopsis thaliana |
2-methyl-3-oxopropanoate + NADH + H+ |
- |
? |
| 1.1.1.31 | (S)-3-hydroxyisobutyrate + NAD+ |
100% activity |
Arabidopsis thaliana |
methylmalonate semialdehyde + NADH + H+ |
- |
? |
| 1.1.1.31 | (S)-methyl-3-hydroxy-2-methylpropionate + NAD+ |
1.2% activity compared to (S)-3-hydroxyisobutyrate |
Arabidopsis thaliana |
? |
- |
? |
| 1.1.1.31 | 3-hydroxy-2-methylpropanoate + NAD+ |
- |
Arabidopsis thaliana |
2-methyl-3-oxopropanoate + NADH + H+ |
- |
? |
| 1.1.1.31 | 3-hydroxypropionate + NAD+ |
13% activity compared to (S)-3-hydroxyisobutyrate |
Arabidopsis thaliana |
malonate semialdehyde + NADH + H+ |
- |
? |
| 1.1.1.31 | more |
no activity with (R)-methyl-3-hydroxy-2-methylpropionate, glycerate, serine, beta-hydroxypyruvate, threonine, 2-hydroxybutyrate, malate, glycolate, beta-hydroxybutyrate, lactate, and 6-phosphogluconate. NADP+ is not a suitable cofactor. Also, FAD, oxidized cytochrome c, as well as the artificial electron acceptors phenazine methosulfate and dichlorophenol indophenol cannot be reduced by the enzyme |
Arabidopsis thaliana |
? |
- |
- |
| 1.1.1.31 | (S)-3-hydroxyisobutyrate + NAD+ |
the enzyme is very specific to (S)-3-hydroxyisobutyrate |
Bacillus cereus |
2-methyl-3-oxopropanoate + NADH + H+ |
- |
? |
| 1.1.1.31 | 3-hydroxy-2-methylpropanoate + NAD+ |
- |
Bacillus cereus |
2-methyl-3-oxopropanoate + NADH + H+ |
- |
r |
