EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.7.8.8 | CDP-diacylglycerol + L-Ser |
- |
Bacillus subtilis |
CMP + 3-O-sn-phosphatidyl-L-serine |
- |
? |
2.7.8.8 | CDP-diacylglycerol + L-Ser |
- |
Escherichia coli |
CMP + 3-O-sn-phosphatidyl-L-serine |
- |
? |
2.7.8.8 | CDP-diacylglycerol + L-Ser |
equilibrium strongly favors synthesis of phosphatidylserine |
Escherichia coli |
CMP + 3-O-sn-phosphatidyl-L-serine |
- |
r |
2.7.8.8 | CDP-diacylglycerol + L-Ser |
reaction proceeds with retention of configuration at phosphorus, which suggests a two-step mechanism involving a phosphatidyl-enzyme intermediate |
Escherichia coli |
CMP + 3-O-sn-phosphatidyl-L-serine |
- |
? |
2.7.8.8 | CDP-diacylglycerol + L-serine |
the enzyme participates in the biosynthesis of phosphatidylethanolamine |
Escherichia coli |
CMP + 3-O-sn-phosphatidyl-L-serine |
- |
? |
2.7.8.8 | CDP-diacylglycerol + L-serine |
increase in activity caused by phosphatidylglycerol and diphosphatidylglycerol is physiologically relevant. It may be part of a regulatory mechanism that keeps the balance between phosphatidylethanolamine and the sum of phosphatidylglycerol and diphosphatidylglycerol |
Escherichia coli |
CMP + 3-O-sn-phosphatidyl-L-serine |
- |
? |
2.7.8.8 | CDP-diacylglycerol + L-serine |
the enzyme catalyzes the first committed step in the biosynthesis of phosphatidylethanolamine |
Escherichia coli |
CMP + 3-O-sn-phosphatidyl-L-serine |
- |
? |
2.7.8.8 | CDP-diacylglycerol + L-serine |
possible regulatory mechanism: cross-feedback regulatory model which assumes two forms of phosphatidylserine synthase, only molecules bound with acidic phospholipids of the membrane are active in phosphatidylserine synthesis, whereas others in the cytoplasm are latent |
Escherichia coli |
CMP + 3-O-sn-phosphatidyl-L-serine |
- |
? |
2.7.8.8 | CDP-diacylglycerol + L-serine |
- |
Arabidopsis thaliana |
CMP + (3-sn-phosphatidyl)-L-serine |
- |
? |
2.7.8.8 | CDP-diacylglycerol + L-serine |
- |
Oryza sativa |
CMP + (3-sn-phosphatidyl)-L-serine |
- |
? |