2.7.8.8	CDP-1,2-bis-O-(oleoyl)-sn-glycerol + L-serine	41% of the activity compared to CDP-1,2-diacylglycerol with fatty acids from lecithin	Escherichia coli	CMP + 1,2-bis-O-(oleoyl)-sn-glycero-3-phospho-L-serine	-	?	420457	
2.7.8.8	CDP-1,2-diacylglycerol + L-serine	fatty acids from lecithin	Escherichia coli	CMP + 1,2-diacyl-sn-glycerol-3-phospho-L-serine	-	?	420459	
2.7.8.8	CDP-1,2-dicaproyl-DL-glycerol + L-Ser	-	Escherichia coli	CMP + 3-O-sn-1,2-dicaproylphosphatidylserine	-	?	358729	
2.7.8.8	CDP-1,2-dipalmitoyl-L-glycerol + L-Ser	-	Escherichia coli	CMP + 1,2-dipalmitoylphosphatidylserine	-	?	358728	
2.7.8.8	CDP-1,2-dipalmitoyl-L-glycerol + L-Ser	-	Vibrio parahaemolyticus	CMP + 1,2-dipalmitoylphosphatidylserine	-	?	358728	
2.7.8.8	CDP-1,2-distearoyl-L-glycerol + L-Ser	-	Vibrio parahaemolyticus	CMP + 1,2-distearoylphosphatidylserine	-	?	459509	
2.7.8.8	CDP-2,3-bis-O-(oleoyl)-sn-glycerol + L-serine	17% of the activity compared to CDP-1,2-diacylglycerol with fatty acids from lecithin	Escherichia coli	CMP + 2,3-bis-O-(oleoyl)-sn-glycero-1-phospho-L-serine	-	?	420461	
2.7.8.8	CDP-diacylglycerol + glycerol	low activity	Escherichia coli	CMP + phosphatidylglycerol	-	?	358730	
2.7.8.8	CDP-diacylglycerol + H2O	-	Escherichia coli	CMP + phosphatidic acid	-	?	358732	
2.7.8.8	CDP-diacylglycerol + H2O	at 1% of the synthetic rate the enzyme catalyzes the hydrolysis of phosphatidylserine to CMP and phosphatidic acid	Escherichia coli	CMP + phosphatidic acid	-	?	358732	
2.7.8.8	CDP-diacylglycerol + L-Ser	-	Bacillus subtilis	CMP + 3-O-sn-phosphatidyl-L-serine	-	?	358720	
2.7.8.8	CDP-diacylglycerol + L-Ser	-	Escherichia coli	CMP + 3-O-sn-phosphatidyl-L-serine	-	?	358720	
2.7.8.8	CDP-diacylglycerol + L-Ser	equilibrium strongly favors synthesis of phosphatidylserine	Escherichia coli	CMP + 3-O-sn-phosphatidyl-L-serine	-	r	358720	
2.7.8.8	CDP-diacylglycerol + L-Ser	reaction proceeds with retention of configuration at phosphorus, which suggests a two-step mechanism involving a phosphatidyl-enzyme intermediate	Escherichia coli	CMP + 3-O-sn-phosphatidyl-L-serine	-	?	358720	
2.7.8.8	CDP-diacylglycerol + L-serine	the enzyme participates in the biosynthesis of phosphatidylethanolamine	Escherichia coli	CMP + 3-O-sn-phosphatidyl-L-serine	-	?	370542	
2.7.8.8	CDP-diacylglycerol + L-serine	increase in activity caused by phosphatidylglycerol and diphosphatidylglycerol is physiologically relevant. It may be part of a regulatory mechanism that keeps the balance between phosphatidylethanolamine and the sum of phosphatidylglycerol and diphosphatidylglycerol	Escherichia coli	CMP + 3-O-sn-phosphatidyl-L-serine	-	?	370542	
2.7.8.8	CDP-diacylglycerol + L-serine	the enzyme catalyzes the first committed step in the biosynthesis of phosphatidylethanolamine	Escherichia coli	CMP + 3-O-sn-phosphatidyl-L-serine	-	?	370542	
2.7.8.8	CDP-diacylglycerol + L-serine	possible regulatory mechanism: cross-feedback regulatory model which assumes two forms of phosphatidylserine synthase, only molecules bound with acidic phospholipids of the membrane are active in phosphatidylserine synthesis, whereas others in the cytoplasm are latent	Escherichia coli	CMP + 3-O-sn-phosphatidyl-L-serine	-	?	370542	
2.7.8.8	CDP-diacylglycerol + L-serine	-	Arabidopsis thaliana	CMP + (3-sn-phosphatidyl)-L-serine	-	?	407177	
2.7.8.8	CDP-diacylglycerol + L-serine	-	Oryza sativa	CMP + (3-sn-phosphatidyl)-L-serine	-	?	407177	
2.7.8.8	CDP-diacylglycerol + L-serine	-	Escherichia coli	CMP + (3-sn-phosphatidyl)-L-serine	-	?	407177	
2.7.8.8	CDP-diacylglycerol + L-serine	-	Oryza sativa Japonica Group	CMP + (3-sn-phosphatidyl)-L-serine	-	?	407177	
2.7.8.8	CDP-diacylglycerol + L-serine	-	Candida albicans	CMP + (3-sn-phosphatidyl)-L-serine	-	?	407177	
2.7.8.8	CDP-diacylglycerol + sn-glycero-3-phosphate	-	Escherichia coli	CMP + phosphatidylglycerophosphate	-	?	358731	
2.7.8.8	CDP-diacylglycerol + sn-glycero-3-phosphate	low activity	Escherichia coli	CMP + phosphatidylglycerophosphate	-	?	358731	
2.7.8.8	CDP-dipalmitoylglycerol + L-serine	-	Vibrio parahaemolyticus	CMP + (3-sn-phosphatidyl)-L-serine	-	?	459512	
2.7.8.8	additional information	the enzyme also catalyzes the exchange reaction between Ser and phosphatidylserine	Escherichia coli	?	-	?	89	
2.7.8.8	additional information	enzyme catalyzes exchange reaction between dCDP-diglyceride and dCDP-diglyceride	Escherichia coli	?	-	?	89	
2.7.8.8	additional information	enzyme catalyzes exchange reaction between CMP and CDP-diglyceride	Escherichia coli	?	-	?	89	
2.7.8.8	additional information	the enzyme is specific for the L-glycerol-3-phosphate isomer of the liponucleotide and does not recognize the D-isomer of the 1-monoacyl derivative	Escherichia coli	?	-	?	89	
2.7.8.8	additional information	very low activity with (less than 10% compared to CDP-1,2-diacylglycerol with fatty acids from lecithin): CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol, CDP-1,2-bis-O-(geranylgeranyl)-sn-glycerol, CDP-2,3-bis-O-(phytanyl)-sn-glycerol	Escherichia coli	?	-	?	89	
2.7.8.8	phosphatidylserine + H2O	-	Escherichia coli	?	-	?	64440