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Search term: NT2/D1 cell

Results 1 - 3 of 3
EC Number Recommended Name Source Tissue Commentary Reference
Show all pathways known for 1.1.1.41Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.41isocitrate dehydrogenase (NAD+) NT2/D1 cell - 741407
Display the word mapDisplay the reaction diagram Show all sequences 3.4.19.12ubiquitinyl hydrolase 1 NT2/D1 cell - 667234
Display the word mapDisplay the reaction diagram Show all sequences 3.4.19.12ubiquitinyl hydrolase 1 NT2/D1 cell down regulation of UCHL1 is detected immediately after oxygen-glucose deprivation treatment and its expression is subsequently restored and increased 6 h after oxygen-glucose deprivation treatment as well as during reoxygenation. A lower level of UCHL1 is detected only in apoptotic cells with severe loss of mitochondrial membrane potential. Down-regulation of endogenous UCHL1 by antisense cDNA in mouse N2a neuroblastoma cells increased the cellย’s sensitivity to oxygen-glucose deprivation. This down-regulation of endogenous UCHL1 leads to the accumulation of p27, suggesting that UCHL1 is an essential gene to maintain cell homeostasis under normal growth and oxidative stress conditions 667234
Results 1 - 3 of 3