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EC Number
Expression
Commentary
Reference
3.6.1.56
down
age-related accumulation of 8-oxoguanine in RNA is correlated with decreased expression of MTH1
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,
716343
3.6.1.56
down
increased amounts of 8-oxoguanine in the RNA, and decreased expression of MTH1 are observed in the hippocampi of patients suffering from Alzheimer's disease
716343
3.6.1.56
up
a statistically significant induction of 8-oxo-dGTPase by 137Cs gamma radiation (given as a single whole-body dose (1 Gy/min)) is found in brains, testes and kidneys but not in lungs, hearts or livers
716889
3.6.1.56
up
oxidative stress in brain induces expression of MTH1 especially in microglia, thus avoiding cellular dysfunction
716299
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