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Results 1 - 4 of 4
EC Number Expression Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.29up after hypoxia treatment the enzyme expression is significantly increased in all analyzed tissues 741826
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.29up at 8 weeks of age the Hif-p4h isoforms 1, 2 and 3 are expressed in the jejunum epithelium at similar levels of 27, 35 and 29 copies/fg RNA. At 3 and 16 weeks of age, Hif-p4h-3 seems to have a slightly higher expression level than the other two isoforms. The caecum epithelium, Hif-p4h-2 has the highest abundance (109 copies/fg RNA input at 8 weeks of age) of the Hif-p4h isoforms, which is significantly higher when compared to Hif-p4h-3 (39 copies/fg RNA input). In the colon epithelium Hif-p4h-2 mRNA has the highest abundance (44 copies/fg RNA input) among the Hif-p4h isoforms, which is significantly higher than that of Hif-p4h-1 (18 copies/fg RNA input) and Fih1 (15 copies/fg RNA input), while the difference between the Hif-p4h-2 and Hif-p4h-3 (30 copies/fg RNA input) mRNA levels do not reach statistical significance 764922
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.29up isozyme PHD3 is induced in cells in hypoxia in a HIF-dependent manner and plays a role in a negative-feedback loop 745510
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.29up the expression of prolyl 4-hydroxylase domain protein 3 (PHD3) increases under hypoxia. Fibrosis improves when PHD3 is overexpressed 764257
Results 1 - 4 of 4