Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
hypoxia-inducible factor-L-proline + 2-oxoglutarate + O2 | Megalobrama amblycephala | - |
hypoxia-inducible factor-trans-4-hydroxy-L-proline + succinate + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Megalobrama amblycephala | A0A140EDB6 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | - |
Megalobrama amblycephala | - |
brain | - |
Megalobrama amblycephala | - |
embryo | detected only in the initial stages of embryo development | Megalobrama amblycephala | - |
gill | - |
Megalobrama amblycephala | - |
heart | - |
Megalobrama amblycephala | - |
intestine | - |
Megalobrama amblycephala | - |
kidney | - |
Megalobrama amblycephala | - |
liver | high expression | Megalobrama amblycephala | - |
muscle | - |
Megalobrama amblycephala | - |
spleen | - |
Megalobrama amblycephala | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hypoxia-inducible factor-L-proline + 2-oxoglutarate + O2 | - |
Megalobrama amblycephala | hypoxia-inducible factor-trans-4-hydroxy-L-proline + succinate + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 26845, calculated from amino acid sequence | Megalobrama amblycephala |
Synonyms | Comment | Organism |
---|---|---|
HIF prolyl hydroxylase | - |
Megalobrama amblycephala |
PHD3 | - |
Megalobrama amblycephala |
Organism | Comment | Expression |
---|---|---|
Megalobrama amblycephala | after hypoxia treatment the enzyme expression is significantly increased in all analyzed tissues | up |
General Information | Comment | Organism |
---|---|---|
physiological function | isoform PHD3 plays important roles in hypoxia response and early embryo development of Megalobrama amblycephala | Megalobrama amblycephala |