EC Number |
Metals/Ions |
Reference |
---|
3.3.2.6 | Br- |
stimulates peptidase and epoxide hydrolase activity (i.e. conversion of leukotriene A4 into leukotriene B4), SCN- most effective, followed by Cl- and Br- |
646992 |
3.3.2.6 | Cl- |
stimulates peptidase activity, not epoxide hydrolase activity (i.e. conversion of leukotriene A4 into leukotriene B4), SCN- most effective, followed by Cl- and Br- |
646992 |
3.3.2.6 | Co2+ |
apoenzyme can be restored by addition of Co2+, peptidase activity exceeds that of enzyme reactivated with zinc |
646986 |
3.3.2.6 | Co2+ |
apoenzyme is inactive and can be reactivated by addition of stoichiometric amounts of zinc and cobalt |
646993 |
3.3.2.6 | thiocyanate |
stimulates peptidase and epoxide hydrolase activity (i.e. conversion of leukotriene A4 into leukotriene B4), SCN- most effective, followed by Cl- and Br- |
646992 |
3.3.2.6 | Zinc |
- |
647009 |
3.3.2.6 | Zinc |
0.8 mol zinc per mol enzyme |
647009 |
3.3.2.6 | Zinc |
apoenzyme is inactive and can be reactivated by addition of stoichiometric amounts of zinc and cobalt |
646993 |
3.3.2.6 | Zinc |
catalytic zinc site with the signature HEXXH-(X)18-E, three zinc binding ligands: His295, His299 and Glu318 |
647015 |
3.3.2.6 | Zinc |
recombinant enzyme: 0.7-1 mol of zinc/mol of enzyme |
646985 |