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Version 2014-12-22
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Details for RNA polymerase V complex
Gene ontology ID
GO:0000419
Definition
RNA polymerase V is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol V is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits
Synonyms
1. DNA-directed RNA polymerase IVb complex
2. DNA-directed RNA polymerase V complex
References
1. GOC: krc
2. GOC: mtg sensu
3. PMID 16140984
4. PMID 19110459
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