Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2',3'-dideoxy-ATP + H2O + a dynein associated with a microtubule at position n
2',3'-dideoxy-ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
2'-dATP + H2O + a dynein associated with a microtubule at position n
2'-dADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
3'-dATP + H2O + a dynein associated with a microtubule at position n
3'-dADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
8-bromo-ATP + H2O + a dynein associated with a microtubule at position n
8-bromo-ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ADP + H2O + a dynein associated with a microtubule at position n
AMP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + + a dynein associated with a microtubule at position n
ADP + phosphate + alpha/beta tubulin heterodimers
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
BODIPY-FL-ATP + H2O + a dynein associated with a microtubule at position n
BODIPY-FL-ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
fluorescent ATP analogue, hydrolysis at 78% of the rate with ATP, without induction of microtubule translocation or sliding disintegration of elastase-treated axonemes. After preincubation with nonhydrolysable adenosine 5'-(beta:gamma-imido)triphosphate, BODIPY-FL-ATP induces sliding disintegration in about 10% of the axonemes
-
-
?
CTP + H2O + a dynein associated with a microtubule at position n
CDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
formycin triphosphate + H2O + a dynein associated with a microtubule at position n
formycin diphosphate + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
GTP + H2O + a dynein associated with a microtubule at position n
GDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
ITP + H2O + a dynein associated with a microtubule at position n
IDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
TTP + H2O + a dynein associated with a microtubule at position n
TDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
UTP + H2O + a dynein associated with a microtubule at position n
UDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
additional information
?
-
2'-dATP + H2O + a dynein associated with a microtubule at position n
2'-dADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
2'-dATP + H2O + a dynein associated with a microtubule at position n
2'-dADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
3'-dATP + H2O + a dynein associated with a microtubule at position n
3'-dADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
3'-dATP + H2O + a dynein associated with a microtubule at position n
3'-dADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Aequipecten sp.
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynactin and cytoplasmic dynein require each other for microtubule plus-end accumulation. The presence of cytoplasmic dynein is also important for the microtubule plus-end accumulation of NADF
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynein is required directly for rotation of the centrosome/nucleus complex onto the proper embryonic axis, for correct chromosome congression, and for timely initiation of anaphase
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
the LC7 light chains of Chlamydomonas flagellar dyneins interact with components required for both motor assembly and regulation
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Chlamydomonas sp.
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Ciona sp.
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Colobocentrotus sp.
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
dynein is a motor protein that moves on microtubules using the energy of adenosine triphosphate hydrolysis
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
dynein is a motor protein that moves on microtubules using the energy of adenosine triphosphate hydrolysis. The alpha-tubulin residues R403 and E416 are critical for ATPase activation and directional movement of dynein. These residues form salt bridges with the residues in the dynein microtubule-binding domain that work in concert to induce registry change in the stalk coiled coil and activate the ATPase. The R403-E3390 salt bridge functions as a switch for this mechanism because of its reversed charge relative to other residues at the interface
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
ATP binding and its hydrolysis only at P1 site (nucleotide-binding/hydrolysis site) are essential for the motor activities of the cytoplasmic dynein and suggests that the other nucleotide-binding/hydrolysis sites regulate the motor activities. Among them, nucleotide binding at the P3 site is not essential but is critical for microtubule-activated ATPase and motile activities of cytoplasmic dynein
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynein has a dominant function in transporting kinetochore microtubule bundles (K fibers) to the centrosomes
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynein-dynactin, Asp, and KLP10A have complex interdependent functions in spindle pole focusing and centrosome attachment
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Drosophila sp. (in: flies)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Drosophila sp. (in: flies)
-
dynein is a primary motor for fast transport of mitochondria in Drosophila motor axons
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Drosophila sp. (in: flies)
-
dynein is required to prevent premature fast mass movement of cytoplasm (cytoplasmic streaming)
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
microtuble activated activity
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
cytoplasmic dynein heavy chain 2.2 is required for flagellar assembly and also participates in maintenance of promastigote cell shape. LmxDHC2.2 is not an essential gene
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Lmxdhc2.1 that encodes cytoplasmic dynein heavy chain 2.1 is an essentail gene in Leishmania
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynein mediates retrograde neurofilament transport within axons and anterograde delivery of NFs from perikarya into axons
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
kinesin I and cytoplasmic dynein orchestrate glucose-stimulated insulin-containing vesicle movements in clonal MIN6 beta-cells. The majority of transport of large dense-core vesicles in beta-cells is mediated by kinesin I, whilst dyneien probably contrtibutes to the recovery of vesicles after rapid kiss-and-run exocytosis
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
the majority of moving phagosomes are minus-end directed, the remainder moves towards microtubule plus-ends and a small subset moves bi-directionally. Minus-end movement showes pharmacological characteristics expected for dyneins, plus-end movement displayed pharmacological properties of kinesin
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
hydrolysis stimulated 2fold by microtubules at an ATP concentration of 4 mM
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
hydrolysis stimulated 2fold by microtubules at an ATP concentration of 4 mM
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
microtuble activated activity
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynein is required for microtubule-dependent movement of late endocytic vesicles
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
model in which both the stalk and the extreme C terminus of the dynein heavy chain control the rate-limiting step of product release in the dynein enzymatic cycle through long range allosteric mechanisms
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynein moves primarily in 8 nm increments through alternating movements of its two motor domains. Dynein steps are variable in their size and direction
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
microtubule-stimulated
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
cytoplasmic dynein is an AAA+ motor responsible for intracellular cargo transport and force generation along microtubules
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
dynein contains multiple ATPase subunits, with AAA1 serving as the primary catalytic site. ATPase activity at AAA3 is also essential for robust motility. The AAA3 domain of cytoplasmic dynein acts as a switch to facilitate microtubule release
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
dynein is responsible for most microtubule minus-end-directed motility. Dynein contains four AAA+ ATPases per motor domain (AAA1-4). The main site of ATP hydrolysis is AAA1. ATP binding to AAA1 induces microtubule release only if AAA3 is in the posthydrolysis state
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
dynein is responsible for most microtubule minus-end-directed motility. Dynein contains four AAA+ ATPases per motor domain (AAA1-4). The main site of ATP hydrolysis is AAA1. ATP binding to AAA1 induces microtubule release only if AAA3 is in the posthydrolysis state
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
cytoplasmic dynein is an AAA+ motor responsible for intracellular cargo transport and force generation along microtubules
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
dynein contains multiple ATPase subunits, with AAA1 serving as the primary catalytic site. ATPase activity at AAA3 is also essential for robust motility. The AAA3 domain of cytoplasmic dynein acts as a switch to facilitate microtubule release
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
the dynein light chain, Dlc1, is required preferentially for achiasmate segregation (segregation of homologous chromosomes in the absence of meiotic recombination), while the dynein heavy chain is required for meiotic chromosome segregation in both the presence and the absence of recombination
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
the cytoplasmic dynein is a non-processive motor at low ATP concentrations. Processivity can be restored even in the absence of dynactin by increasing the ATP concentration to 0.1 mM
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
most of the force-producing activity resides in the beta-heavy chain beta/gamma-dimer. The alpha-heavy chain serves to hold the dynein complex very near the surface of the microtubule track
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Unio sp.
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
cytoplasmic dynein is the sole motor for microtubule-based ER motility throughout the early stages of development
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynein is required for formation and early maintenance of the vegetal microtubule array
-
-
?
CTP + H2O + a dynein associated with a microtubule at position n
CDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
44% activity compared with ATP
-
?
CTP + H2O + a dynein associated with a microtubule at position n
CDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
CTP + H2O + a dynein associated with a microtubule at position n
CDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
GTP + H2O + a dynein associated with a microtubule at position n
GDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
86% activity compared with ATP
-
?
GTP + H2O + a dynein associated with a microtubule at position n
GDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
GTP + H2O + a dynein associated with a microtubule at position n
GDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
TTP + H2O + a dynein associated with a microtubule at position n
TDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
37% activity compared with ATP
-
?
TTP + H2O + a dynein associated with a microtubule at position n
TDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
UTP + H2O + a dynein associated with a microtubule at position n
UDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
UTP + H2O + a dynein associated with a microtubule at position n
UDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
additional information
?
-
-
microtubules simultaneously accelerate the ATPase activity not only at the primary site but also at other site(s) in the dynein motor domain
-
-
?
additional information
?
-
-
according to power stroke model of dynein, the recovery stroke at the first isomerization step proceeds quickly at about 180 per s, whereas the power stroke at the second isomerization step is very slow with about 0.2 per s in the absence of microtubules. The presence of microtubules accelerates the second but not the first step
-
-
?
additional information
?
-
-
at most of the intermediate states in the ATPase cycle, two mechanical processes proceed simultaneously: the motor domain in the poststroke state binds strongly to the microtubule with a Kd of 0.2 microM, whereas most of the motor domains in the prestroke state bind weakly to the microtubule with a Kd of >10 microM. The timings of the microtubule affinity change and tail swing are staggered at the recovery stroke step in which the tail swings from the poststroke to the prestroke position
-
-
?
additional information
?
-
-
robust microtubule sliding of dynein is driven by the power stroke of dynein tail. Slow microtubule sliding is independent of dynein orientation on a glass surface and is mechanically distinct from the sliding driven by the powerstroke of the tail
-
-
?
additional information
?
-
-
the cytoplasmic dynein light chain Tctex-1 plays a key role in multiple steps of hippocampal neuron development, including initial neurite sprouting, axon specification, and later dendritic elaboration. The neuritogenic effects elicited by Tctex-1 are independent from its cargo adaptor role for dynein motor transport. the selective high level of Tctex-1 at the growth cone of growing axons drives fast neurite extension by modulating actin dynamics and also Rac1 activity: Tctex-1 may act as a regulatory link between the microtubule and microfilament cytoskeleton
-
-
?
additional information
?
-
-
dynein intermediate chain isoforms define dynein populations that are selectively recruited to transport distinct cargoes. Neurotrophin receptor tyrosine kinase B signaling endosomes are transported by cytoplasmic dynein containing the neuron-specific intermediate chain-1B isoform and not by dynein containing the ubiquitous intermediate chain-2C isoform. Organelles containing tyrosine kinase B also contain dynein with intermediate chain-1 but not intermediate chain-2 isoforms
-
-
?
additional information
?
-
-
both noncatalytic ATP binding and stable ADP binding, in addition to ATP hydrolysis, are involved in the regulation of the chemo-mechanical transduction in axonemial dynein
-
-
?
additional information
?
-
-
cytoplasmic dynein may play structural and functional roles in the postsynaptic terminal
-
-
?
additional information
?
-
-
measurement of mechanical properties of single dynein molecules. the velocity of dynein movement is around 800 nm/s, the maximum force is 7-8 pN and independent of the ATP concentration. Dynein exhibits forward and backward steps of 8 nm, independent of load. The large dynein heads may take 16 nm steps by using an overlapping hand-over-hand mechanism
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
additional information
?
-
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Aequipecten sp.
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynactin and cytoplasmic dynein require each other for microtubule plus-end accumulation. The presence of cytoplasmic dynein is also important for the microtubule plus-end accumulation of NADF
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynein is required directly for rotation of the centrosome/nucleus complex onto the proper embryonic axis, for correct chromosome congression, and for timely initiation of anaphase
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
the LC7 light chains of Chlamydomonas flagellar dyneins interact with components required for both motor assembly and regulation
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Ciona sp.
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Colobocentrotus sp.
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
dynein is a motor protein that moves on microtubules using the energy of adenosine triphosphate hydrolysis
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynein has a dominant function in transporting kinetochore microtubule bundles (K fibers) to the centrosomes
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynein-dynactin, Asp, and KLP10A have complex interdependent functions in spindle pole focusing and centrosome attachment
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Drosophila sp. (in: flies)
-
dynein is a primary motor for fast transport of mitochondria in Drosophila motor axons
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Drosophila sp. (in: flies)
-
dynein is required to prevent premature fast mass movement of cytoplasm (cytoplasmic streaming)
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
cytoplasmic dynein heavy chain 2.2 is required for flagellar assembly and also participates in maintenance of promastigote cell shape. LmxDHC2.2 is not an essential gene
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Lmxdhc2.1 that encodes cytoplasmic dynein heavy chain 2.1 is an essentail gene in Leishmania
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynein mediates retrograde neurofilament transport within axons and anterograde delivery of NFs from perikarya into axons
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
kinesin I and cytoplasmic dynein orchestrate glucose-stimulated insulin-containing vesicle movements in clonal MIN6 beta-cells. The majority of transport of large dense-core vesicles in beta-cells is mediated by kinesin I, whilst dyneien probably contrtibutes to the recovery of vesicles after rapid kiss-and-run exocytosis
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
the majority of moving phagosomes are minus-end directed, the remainder moves towards microtubule plus-ends and a small subset moves bi-directionally. Minus-end movement showes pharmacological characteristics expected for dyneins, plus-end movement displayed pharmacological properties of kinesin
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynein is required for microtubule-dependent movement of late endocytic vesicles
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
model in which both the stalk and the extreme C terminus of the dynein heavy chain control the rate-limiting step of product release in the dynein enzymatic cycle through long range allosteric mechanisms
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
cytoplasmic dynein is an AAA+ motor responsible for intracellular cargo transport and force generation along microtubules
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
cytoplasmic dynein is an AAA+ motor responsible for intracellular cargo transport and force generation along microtubules
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
the dynein light chain, Dlc1, is required preferentially for achiasmate segregation (segregation of homologous chromosomes in the absence of meiotic recombination), while the dynein heavy chain is required for meiotic chromosome segregation in both the presence and the absence of recombination
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
Unio sp.
-
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
cytoplasmic dynein is the sole motor for microtubule-based ER motility throughout the early stages of development
-
-
?
ATP + H2O + a dynein associated with a microtubule at position n
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
dynein is required for formation and early maintenance of the vegetal microtubule array
-
-
?
additional information
?
-
-
microtubules simultaneously accelerate the ATPase activity not only at the primary site but also at other site(s) in the dynein motor domain
-
-
?
additional information
?
-
-
dynein intermediate chain isoforms define dynein populations that are selectively recruited to transport distinct cargoes. Neurotrophin receptor tyrosine kinase B signaling endosomes are transported by cytoplasmic dynein containing the neuron-specific intermediate chain-1B isoform and not by dynein containing the ubiquitous intermediate chain-2C isoform. Organelles containing tyrosine kinase B also contain dynein with intermediate chain-1 but not intermediate chain-2 isoforms
-
-
?
additional information
?
-
-
cytoplasmic dynein may play structural and functional roles in the postsynaptic terminal
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
122000
-
alpha1,alpha2,IC1,IC2,IC3,LC1-LC4, 1 * 333000 + 1 * 320000 + 1 * 122000 + 1 * 90000 + 1 * 76000 + 1 * 76000 + 4 * 24000-14000, 21S dynein 1, SDS-PAGE
130000
-
alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
14000
-
alpha1,alpha2,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 96000 + 1 * 82000 + 1* 18000 + 1 * 16500 + 1 * 14000, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
140000
-
alpha,beta, IC1,IC2, 1 * 420000 + 1 * 360000 + 1 * 140000 + 1 * 91000, unidentified lower weight peptides
14500
-
alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
16000
-
alpha,LC1, 1 * 440000 + 1 * 16000, 18S dynein, alpha subunit
18000
-
alpha,LC1,LC2, 1 * 400000 + 1 * 22000 + 1 * 18000, 12S dynein
2000000
-
30S dynein, scanning transmission electron microscopy
21000
-
alpha1,alpha2,IC2,IC3,LC1,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 94000 + 1 * 80000 + 1* 27000 + 1 * 21000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
22000
-
alpha,LC1,LC2, 1 * 400000 + 1 * 22000 + 1 * 18000, 12S dynein
333000
-
alpha1,alpha2,IC1,IC2,IC3,LC1-LC4, 1 * 333000 + 1 * 320000 + 1 * 122000 + 1 * 90000 + 1 * 76000 + 1 * 76000 + 4 * 24000-14000, 21S dynein 1, SDS-PAGE
380000
-
cytoplasmic dynein motor domain
390000
-
alpha, 1 * 390000, 12S dynein, no clear intermediate peptides, unidentified lower weight peptides
400000
-
alpha,LC1,LC2, 1 * 400000 + 1 * 22000 + 1 * 18000, 12S dynein
440000
-
alpha,LC1, 1 * 440000 + 1 * 16000, 18S dynein, alpha subunit
500000
-
12S dynein, scanning transmission electron microscopy
550000
-
12S sucrose density gradient fraction, calculated from sedimentation constant (12.3 S) and Stokes radius (10.2 nm)
69000
-
alpha, IC1,IC2,LC1-7, 1 * 420000 + 1 * 78000 + 1 * 69000 + 7 * 8000-20000, 18S dynein, beta subunit
720000
-
12S dynein 2, analytical gel electrophoreses
76000
-
alpha1,alpha2,IC1,IC2,IC3,LC1-LC4, 1 * 333000 + 1 * 320000 + 1 * 122000 + 1 * 90000 + 1 * 76000 + 1 * 76000 + 4 * 24000-14000, 21S dynein 1, SDS-PAGE
80000
-
alpha1,alpha2,IC2,IC3,LC1,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 94000 + 1 * 80000 + 1* 27000 + 1 * 21000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
82000
-
alpha1,alpha2,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 96000 + 1 * 82000 + 1* 18000 + 1 * 16500 + 1 * 14000, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
82500
-
alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
91000
-
alpha,beta, IC1,IC2, 1 * 420000 + 1 * 360000 + 1 * 140000 + 1 * 91000, unidentified lower weight peptides
94000
-
alpha1,alpha2,IC2,IC3,LC1,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 94000 + 1 * 80000 + 1* 27000 + 1 * 21000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
1250000
-
18S dynein, scanning transmission electron microscopy
1250000
-
21S dynein 1, analytical centrifugation, sedimentation-diffusion, sedimentation equilibrium
16500
-
alpha1,alpha2,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 96000 + 1 * 82000 + 1* 18000 + 1 * 16500 + 1 * 14000, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
16500
-
alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
17000
-
alpha1,alpha2,IC2,IC3,LC1,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 94000 + 1 * 80000 + 1* 27000 + 1 * 21000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
17000
-
alpha1,alpha2,IC2,IC3,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 90000 + 1 * 78000 + 1* 20000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
320000
-
alpha,beta,gamma, 1 * 385000 + 1 * 360000 + 1 * 320000, only heavy chains determined, alpha and gamma band slit into doublets, several unidentified lower molecular weight polypeptides
320000
-
alpha,beta,gamma, 1 * 385000 + 1 * 360000 + 1 * 320000, only heavy chains determined, alpha and gamma band slit into doublets, several unidentified lower molecular weight polypeptides
320000
-
alpha1,alpha2,IC1,IC2,IC3,LC1-LC4, 1 * 333000 + 1 * 320000 + 1 * 122000 + 1 * 90000 + 1 * 76000 + 1 * 76000 + 4 * 24000-14000, 21S dynein 1, SDS-PAGE
360000
-
alpha,beta,gamma, 1 * 385000 + 1 * 360000 + 1 * 320000, only heavy chains determined, alpha and gamma band slit into doublets, several unidentified lower molecular weight polypeptides
360000
-
alpha,beta,gamma, 1 * 385000 + 1 * 360000 + 1 * 320000, only heavy chains determined, alpha and gamma band slit into doublets, several unidentified lower molecular weight polypeptides
360000
-
alpha,beta, IC1,IC2, 1 * 420000 + 1 * 360000 + 1 * 140000 + 1 * 91000, unidentified lower weight peptides
385000
-
alpha,beta,gamma, 1 * 385000 + 1 * 360000 + 1 * 320000, only heavy chains determined, alpha and gamma band slit into doublets, several unidentified lower molecular weight polypeptides
385000
-
alpha,beta,gamma, 1 * 385000 + 1 * 360000 + 1 * 320000, only heavy chains determined, alpha and gamma band slit into doublets, several unidentified lower molecular weight polypeptides
420000
-
alpha,beta, IC1,IC2, 1 * 420000 + 1 * 360000 + 1 * 140000 + 1 * 91000, unidentified lower weight peptides
420000
-
alpha, IC1,IC2,LC1-7, 1 * 420000 + 1 * 78000 + 1 * 69000 + 7 * 8000-20000, 18S dynein, beta subunit
430000
-
alpha1,alpha2,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 96000 + 1 * 82000 + 1* 18000 + 1 * 16500 + 1 * 14000, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
430000
-
alpha1,alpha2,IC2,IC3,LC1,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 94000 + 1 * 80000 + 1* 27000 + 1 * 21000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
430000
-
alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
430000
-
alpha1,alpha2,IC2,IC3,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 90000 + 1 * 78000 + 1* 20000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
450000
-
alpha1,alpha2,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 96000 + 1 * 82000 + 1* 18000 + 1 * 16500 + 1 * 14000, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
450000
-
alpha1,alpha2,IC2,IC3,LC1,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 94000 + 1 * 80000 + 1* 27000 + 1 * 21000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
450000
-
alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
450000
-
alpha1,alpha2,IC2,IC3,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 90000 + 1 * 78000 + 1* 20000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
78000
-
alpha1,alpha2,IC2,IC3,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 90000 + 1 * 78000 + 1* 20000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
78000
-
alpha, IC1,IC2,LC1-7, 1 * 420000 + 1 * 78000 + 1 * 69000 + 7 * 8000-20000, 18S dynein, beta subunit
90000
-
alpha1,alpha2,IC2,IC3,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 90000 + 1 * 78000 + 1* 20000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
90000
-
alpha1,alpha2,IC1,IC2,IC3,LC1-LC4, 1 * 333000 + 1 * 320000 + 1 * 122000 + 1 * 90000 + 1 * 76000 + 1 * 76000 + 4 * 24000-14000, 21S dynein 1, SDS-PAGE
96000
-
alpha1,alpha2,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 96000 + 1 * 82000 + 1* 18000 + 1 * 16500 + 1 * 14000, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
96000
-
alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.