Activating Compound | Comment | Organism | Structure |
---|---|---|---|
tubulin | from porcine brain, 3fold increase of 30S dynein activity at pH 10, maximum at a tubulin/30S dynein molar ratio of 10 | Tetrahymena pyriformis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.01 | - |
ATP | 30S dynein, in the absence of tubulin, 1 mM KCl | Tetrahymena pyriformis | |
0.23 | - |
ATP | 30S dynein, in the presence of tubulin, 1 mM KCl | Tetrahymena pyriformis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + a dynein associated with a microtubule at position n | Tetrahymena pyriformis | - |
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end) | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Tetrahymena pyriformis | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
2.5 | - |
30S dynein, in the presence of tubulin | Tetrahymena pyriformis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + H2O + a dynein associated with a microtubule at position n | - |
Tetrahymena pyriformis | AMP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end) | - |
? | |
ATP + H2O + a dynein associated with a microtubule at position n | - |
Tetrahymena pyriformis | ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end) | - |
? | |
CTP + H2O + a dynein associated with a microtubule at position n | - |
Tetrahymena pyriformis | CDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end) | - |
? | |
GTP + H2O + a dynein associated with a microtubule at position n | - |
Tetrahymena pyriformis | GDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end) | - |
? | |
ITP + H2O + a dynein associated with a microtubule at position n | - |
Tetrahymena pyriformis | IDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end) | - |
? | |
UTP + H2O + a dynein associated with a microtubule at position n | - |
Tetrahymena pyriformis | UDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end) | - |
? |