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The enzyme acts in the opposite direction. The enzymes from the bacteria Escherichia coli and Pseudomonas sp. Y2 also have the activity of EC 220.127.116.11 (3-oxoadipyl-CoA thiolase).
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The enzyme appears in viruses and cellular organisms
2,3-didehydroadipoyl-CoA + acetyl-CoA = CoA + 3-oxo-5,6-didehydrosuberoyl-CoA
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