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Information on EC 1.14.13.240 - 2-polyprenylphenol 6-hydroxylase

for references in articles please use BRENDA:EC1.14.13.240

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IUBMB Comments

Contains FAD. The enzyme from the bacterium Escherichia coli (UbiI) catalyses the first hydroxylation during the aerobic biosynthesis of ubiquinone. The enzyme from the bacterium Neisseria meningitidis (UbiM) can also catalyse the two additional hydroxylations that occur in the pathway (cf. EC 1.14.99.60, 3-demethoxyubiquinol 3-hydroxylase).

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
2-octaprenylphenol hydroxylase, HMPREF0602_0026, ubiI, ubiM, visC, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-(all-trans-polyprenyl)phenol + NADPH + H+ + O2 = 3-(all-trans-polyprenyl)benzene-1,2-diol + NADP+ + H2O
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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