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The enzyme, found in the bacterium Bacillus subtilis, has no activity with NAD+ [cf. EC 18.104.22.1680, scyllo-inositol 2-dehydrogenase (NAD+)].
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
, NADP+-dependent SI dehydrogenase, yulF
scyllo-inositol + NADP+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+
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