Sequence of DCPS_CAEEL
EC Number:3.6.1.59
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase
G5EFS4
Caenorhabditis elegans
311
36477
Reaction
a 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] + H2O = N7-methylguanosine 5'-phosphate + a 5'-diphospho-[mRNA]
Other sequences found for EC No. 3.6.1.59
General information:
Sequence
0 MKRIADEELV REERAEESTQ KWLQDAKFQE ILGADSSHKS LFVLLSHPDG SQGILLANKS
60 PFSEEKSDIE KLLATAQLQE ISRNDIFGSY NIEIDPKLNL LKSQLIYPIN DRLIAKYRQE
120 EKFVIRETPE LYETVTRPYI EKYQLNLNWV YNCLEKRSEV DKIVFEDPDN ENGFVLLQDI
180 KWDGKTLENL YVLAICHRHG LKSVRDLTGD DLEMLYNMRD KSLEAINQKY GLKTDQIKCY
240 FHYQPSFYHL HVHFINLKYD APASTTMSAI LLDDVINNLE LNPEHYKKST LTFTRKNGDK
300 LMEMFREALK N
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1176438
Kwasnicka D.A.,Krakowiak A.,Thacker C.,Brenner C.,Vincent S.R.
Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1.
J. Biol. Chem.
278
39051-39058
2003
1176439
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science
282
2012-2018
1998
1176440
Cohen L.S.,Mikhli C.,Friedman C.,Jankowska-Anyszka M.,Stepinski J.,Darzynkiewicz E.,Davis R.E.
Nematode m7GpppG and m3(2,2,7)GpppG decapping: activities in Ascaris embryos and characterization of C. elegans scavenger DcpS.
RNA
10
1609-1624
2004
1176441
Wypijewska A.,Bojarska E.,Lukaszewicz M.,Stepinski J.,Jemielity J.,Davis R.E.,Darzynkiewicz E.
7-Methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (dcpS) enzymes and potently inhibits their activity.
Biochemistry
51
8003-8013
2012
