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Sequence of ACBO_ACTS5

EC Number:5.1.3.35

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
2-epi-5-epi-valiolone 7-phosphate 2-epimerase
Q8RMD1
Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)
270
28458
Reaction
2-epi-5-epi-valiolone 7-phosphate = 5-epi-valiolone 7-phosphate
Other sequences found for EC No. 5.1.3.35

General information:

Sequence
show sequence in fasta format
  0 MTCRVGLTEW RLAPSGAAAI RLAAAVGADG IQLDFGGPGR GVLVDGPGRA GQLRAVADEA
 60 GVDLLALAGN LLNDIGLTSQ PAVVQPVLAR LADTATELGV PLLIVPSFRR SAITDAMSFT
120 RTAAALRWAV SLAEARGIVL ASENVLPPAR ARQLVEEVGS PAFRLLLDTF NPVRYGLDPA
180 WLATELRPWW ADQIHLKDGP PDTGPSPLLG AGQGGVRRTL TALRGSPAPV RALVLENDYR
240 DGHGARLRAD LEWARRAAVN ARESEKGKLT
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
764609
Stratmann A.,Mahmud T.,Lee S.,Distler J.,Floss H.G.,Piepersberg W.
The AcbC protein from Actinoplanes species is a C7-cyclitol synthase related to 3-dehydroquinate synthases and is involved in the biosynthesis of the alpha-glucosidase inhibitor acarbose.
J. Biol. Chem.
274
10889-10896
1999
764610
Zhang C.S.,Podeschwa M.,Altenbach H.J.,Piepersberg W.,Wehmeier U.F.
The acarbose-biosynthetic enzyme AcbO from Actinoplanes sp. SE 50/110 is a 2-epi-5-epi-valiolone-7-phosphate 2-epimerase.
FEBS Lett.
540
47-52
2003