EC Number |
Protein Variants |
Reference |
---|
3.6.1.56 | A84G |
the mutant shows about 70% of wild type activity |
757347 |
3.6.1.56 | A84G/G90E |
the mutant shows about 110% of wild type activity |
757347 |
3.6.1.56 | D119A |
mutant enzyme shows no hydrolytic activity with 2-hydroxy-dATP. Specific activity with 8-oco-dGTP is 139% of wild-type activity |
668195 |
3.6.1.56 | D119A |
mutation completely abolishes the 2-hydroxy-dATP-hydrolyzing ability, whereas the mutant retains substantial levels of 8-oxo-dGTPase activity |
715460 |
3.6.1.56 | D119A |
the mutant enzyme has about half of the wild-type activity for 8-oxo-dGTP but shows almost no activity for 2-hydroxy-dATP |
715467 |
3.6.1.56 | D119N |
mutation completely abolishes the 2-hydroxy-dATP-hydrolyzing ability, whereas the mutant retains substantial levels of 8-oxo-dGTPase activity |
715460 |
3.6.1.56 | D119N |
the mutant enzyme has about half of the wild-type activity for 8-oxo-dGTP but shows almost no activity for 2-hydroxy-dATP |
715467 |
3.6.1.56 | D120A |
the mutant shows 8% of wild type activity |
757187 |
3.6.1.56 | D120N |
the mutant shows 4% of wild type activity |
757187 |
3.6.1.56 | G90E |
the mutant shows about 130% of wild type activity |
757347 |