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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.6C70A/C72H/C85A/C88H mutant enzyme is defective in intrinsic termination and antitermination in vitro. Mutation likely causes a recessive-lethal phenotype 662629
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.6C70H mutant enzyme terminates more poorly than wild-type enzyme on put(-) templates, and responds weakly on put. Mutation likely causes a recessive-lethal phenotype 662629
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.6C72H mutant enzyme terminates more poorly than wild-type enzyme on put(-) templates, and responds weakly on put. Mutation likely causes a recessive-lethal phenotype 662629
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.6C85H mutant enzyme terminates more poorly than wild-type enzyme on put(-) templates, and responds weakly on put. Mutation likely causes a recessive-lethal phenotype 662629
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.6D421A mutation results in an enzyme with reduced activity and altered patterns of transcription 643584
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.6D421T mutation results in an enzyme with reduced activity and altered patterns of transcription 643584
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.6D505A mutation in subunit Rpb2, the mutant shows a weak defect in the escape from a transcriptional stall at A20 -, 706600
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.6del70-88insGGGG mutant enzyme terminates more poorly than wild-type enzyme on put(-) templates, and responds weakly on put. Mutation likely causes a recessive-lethal phenotype 662629
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.6del74-84insGGGG mutant enzyme terminates more poorly than wild-type enzyme on put(-) templates, and responds weakly on put. Mutation likely causes a recessive-lethal phenotype 662629
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.6E1028Q mutation in subunit Rpb2, the mutant shows transcription elongation defects 706600
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