EC Number   |
Protein Variants |
Reference |
|---|
   1.16.3.4 | C500S |
mutant designed to incapacitate binding of the T1 copper, mutant protein does not support resistance to copper toxicity when placed in a cell line missing a functional CueO gene |
763201 |
| 1.16.3.4 | C500S |
mutation leads to loss of the T1 copper |
-, 763245, 763246 |
| 1.16.3.4 | D360A |
mutation in labile copper coordination sphere, inactive |
763235 |
| 1.16.3.4 | D360M |
mutation at sites Cu5 |
763429 |
| 1.16.3.4 | D439A |
3.8-4.2 copper atoms per protein molecule, similar to wild-type |
762693 |
| 1.16.3.4 | D439A |
mutation in labile copper coordination sphere, 3-4fold increase in Km value for Cu2+ |
763235 |
| 1.16.3.4 | D439A |
positive shift in the redox potential of this copper center and enhanced oxidase activity |
762721 |
| 1.16.3.4 | D507A |
about 10% increase in specific activity |
762692 |
| 1.16.3.4 | D507N |
about 80% increase in specific activity |
762692 |
| 1.16.3.4 | E506A |
mutation results in the formation of a compensatory hydrogen bond network with one or two extra water molecules |
762692 |
