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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.B2R360A enzyme loses the ability to effectively oxidize chloride but can still function as bromoperoxidase 348336
Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.B2R360C/I391V 5fold increase in brominating activity at pH 8 674779
Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.B2R490A enzyme loses the ability to effectively oxidize chloride but can still function as bromoperoxidase 348336
Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.B2S402A 1.8% of the activity of wild-type enzyme (chlorination of monochlorodimedone), mutation decreases activity, mutant enzyme still catalyzes efficiently oxidation of both Cl- and Br- 658904
Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.B2S427H the mutant shows nearly wild type activity at approximately 70% in the monochlorodimedone assay but is unable to catalyze the conversion of 3 into 4 or 5. Instead, the mutant exclusively catalyzes the formation of 3-based bromohydrins 725200
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