EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.1.1.106 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
30619475 |
Mono-ADP-Ribosylhydrolase MACROD2 Is Dispensable for Murine Responses to Metabolic and Genotoxic Insults. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
2
1
0 |
| 3.1.1.106 | Fatty Liver |
25975270 |
Loss of the Mono-ADP-ribosyltransferase, Tiparp, Increases Sensitivity to Dioxin-induced Steatohepatitis and Lethality. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
1
2
0 |
| 3.1.1.106 | Graves Disease |
27304844 |
Association of Polymorphisms in MACRO Domain Containing 2 With Thyroid-Associated Orbitopathy. |
causal interaction
unassigned |
4
0 |
| 3.1.1.106 | Insulin Resistance |
30343302 |
High Genetic Risk Scores of ASIC2, MACROD2, CHRM3, and C2orf83 Genetic Variants Associated with Polycystic Ovary Syndrome Impair Insulin Sensitivity and Interact with Energy Intake in Korean Women. |
diagnostic usage
unassigned |
3
0 |
| 3.1.1.106 | Intellectual Disability |
30619475 |
Mono-ADP-Ribosylhydrolase MACROD2 Is Dispensable for Murine Responses to Metabolic and Genotoxic Insults. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
2
1
0 |
| 3.1.1.106 | Intellectual Disability |
31055587 |
Intragenic Deletion in MACROD2: A Family with Complex Phenotypes Including Microcephaly, Intellectual Disability, Polydactyly, Renal and Pancreatic Malformations. |
diagnostic usage
unassigned |
3
0 |
| 3.1.1.106 | Microcephaly |
31055587 |
Intragenic Deletion in MACROD2: A Family with Complex Phenotypes Including Microcephaly, Intellectual Disability, Polydactyly, Renal and Pancreatic Malformations. |
diagnostic usage
unassigned |
3
0 |
| 3.1.1.106 | Neoplasm Metastasis |
25422431 |
MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
2
1 |
| 3.1.1.106 | Neoplasm Metastasis |
32257385 |
MACROD2 deficiency promotes hepatocellular carcinoma growth and metastasis by activating GSK-3?/?-catenin signaling. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
1
0 |
| 3.1.1.106 | Neoplasms |
23805207 |
Two Distinct Categories of Focal Deletions in Cancer Genomes. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
