EC Number   |
Turnover Number Minimum [1/s] |
Turnover Number Maximum [1/s] |
Substrate |
Reference |
|---|
    4.2.1.22 | 19.7 |
- |
L-serine |
wild-type enzyme, 37°C, presence of S-adenosyl-L-methionine |
650017 |
| 4.2.1.22 | 21 |
- |
L-serine |
pH 6.8, 37°C, full length enzyme after L-serine pre-treatment |
649869 |
| 4.2.1.22 | 21.5 |
- |
L-homocysteine |
pH 8.6, 37°C |
650216 |
| 4.2.1.22 | 21.5 |
- |
L-serine |
wild-type enzyme, pH 8.6, 37°C |
650238 |
| 4.2.1.22 | 26.78 |
- |
L-homocysteine |
cosubstrate L-cysteine, presence of S-adenosyl-L-methionine, pH 7.4, 37°C |
746768 |
| 4.2.1.22 | 31.34 |
- |
L-cysteine |
cosubstrate L-homocysteine, presence of S-adenosyl-L-methionine, pH 7.4, 37°C |
746768 |
| 4.2.1.22 | 32.1 |
- |
homocysteine |
I435T mutant, 37°C, presence of S-adenosyl-L-methionine |
650017 |
| 4.2.1.22 | 34 |
- |
homocysteine |
wild-type enzyme, 37°C, presence of S-adenosyl-L-methionine |
650017 |
| 4.2.1.22 | 39 |
- |
L-serine |
pH 6.8, 37°C, full length enzyme after homocysteine pre-treatment |
649869 |
| 4.2.1.22 | 45 |
- |
L-serine |
pH 6.8, 37°C, deltaC143 mutant after homocysteine pre-treatment |
649869 |
