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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
6.4.1.3
acetyl-CoA + CO2
the enzyme has a preference for propionyl-CoA over acetyl-CoA as the substrate
Ruegeria pomeroyi
?
-
?
6.4.1.3
acetyl-CoA + CO2
the wild type enzyme shows no activity with acetyl-CoA, but mutant enzyme D422I does
Streptomyces coelicolor
?
-
?
6.4.1.3
ATP + acetyl-CoA + HCO3-
-
Mycolicibacterium phlei
ADP + phosphate + malonyl-CoA
-
?
6.4.1.3
ATP + acetyl-CoA + HCO3-
-
Leptospira interrogans
ADP + phosphate + malonyl-CoA
-
?
6.4.1.3
ATP + acetyl-CoA + HCO3-
no other acetyl-CoA carboxylase detected in this organism
Mycolicibacterium smegmatis
ADP + phosphate + malonyl-CoA
-
?
6.4.1.3
ATP + acetyl-CoA + HCO3-
at 0.7% of the velocity compared to propanoyl-CoA
Sus scrofa
ADP + phosphate + malonyl-CoA
-
?
6.4.1.3
ATP + acetyl-CoA + HCO3-
at a rate 1.5% that obtained for propionyl-CoA
Homo sapiens
ADP + phosphate + malonyl-CoA
-
?
6.4.1.3
ATP + acetyl-CoA + HCO3-
EC 6.4.1.2 activity
Myxococcus xanthus
ADP + phosphate + malonyl-CoA
-
?
6.4.1.3
ATP + acetyl-CoA + HCO3-
EC 6.4.1.2 activity
Chloroflexus aurantiacus
ADP + phosphate + malonyl-CoA
-
?
6.4.1.3
ATP + acetyl-CoA + HCO3-
EC 6.4.1.2 activity
Metallosphaera sedula
ADP + phosphate + malonyl-CoA
-
?
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