EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
5.4.99.7 | (3R)-Squalene epoxide |
- |
Methylococcus capsulatus |
Epilanosterol |
- |
? |
5.4.99.7 | (3S)-2,3-epoxy-2,3-dihydrosqualene |
- |
Homo sapiens |
lanosterol |
- |
? |
5.4.99.7 | (3S)-2,3-epoxy-2,3-dihydrosqualene |
- |
Sus scrofa |
lanosterol |
- |
? |
5.4.99.7 | (3S)-2,3-epoxy-2,3-dihydrosqualene |
- |
Saccharomyces cerevisiae |
lanosterol |
- |
? |
5.4.99.7 | (3S)-2,3-epoxy-2,3-dihydrosqualene |
- |
Arabidopsis thaliana |
lanosterol |
- |
r |
5.4.99.7 | (3S)-2,3-epoxy-2,3-dihydrosqualene |
- |
Ganoderma lucidum |
lanosterol |
- |
r |
5.4.99.7 | (3S)-2,3-epoxy-2,3-dihydrosqualene |
- |
Solanum tuberosum |
lanosterol |
- |
r |
5.4.99.7 | (3S)-2,3-epoxy-2,3-dihydrosqualene |
reaction of wild-type enzyme |
Saccharomyces cerevisiae |
lanosterol |
- |
? |
5.4.99.7 | (3S)-2,3-epoxy-2,3-dihydrosqualene |
reaction of wild-type enzyme, via intermediates parkeol and protosta-12,24-dien-3-beta-ol |
Homo sapiens |
lanosterol |
- |
? |
5.4.99.7 | (3S)-2,3-epoxy-2,3-dihydrosqualene |
the enzyme performs the polycyclization reaction by folding the substrate in a chair-boat-chair-chair conformation |
Sus scrofa |
lanosterol |
- |
? |