EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
4.3.3.6 | D-ribulose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine |
preference of D-ribose 5-phosphate compared to D-ribulose 5-phosphate |
Bacillus subtilis |
? |
- |
? |
4.3.3.6 | more |
BtrC2 shows no catalytic activity as 2-deoxy-scyllo-inosose (DOI) synthase |
Niallia circulans |
? |
- |
? |
4.3.3.6 | more |
the enzyme catalyzes the conversion of ribose 5-phosphate and glyceraldehyde 3-phosphate to pyridoxal 5'-phosphate |
Bacillus subtilis |
? |
- |
? |
4.3.3.6 | more |
BtrC2 shows no catalytic activity as 2-deoxy-scyllo-inosose (DOI) synthase |
Niallia circulans SANK 72073 |
? |
- |
? |
4.3.3.6 | L-glutamine + H2O |
- |
Geobacillus kaustophilus |
L-glutamate + NH3 |
- |
? |
4.3.3.6 | L-glutamine + H2O |
two proteins form a complex that functions as a glutamine amidotransferase, with YaaE as the glutaminase domain and YaaD as the acceptor and pyridoxal 5'-phosphate synthesis domain. Glutaminase activity of YaaE is only detected in the presence of its partner protein YaaD. A 1:1 stoichiometry of both proteins appears to be optimal for activity |
Bacillus subtilis |
L-glutamate + NH3 |
- |
? |
4.3.3.6 | D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 |
- |
Geobacillus kaustophilus |
pyridoxal 5'-phosphate + 4 H2O + phosphate |
- |
? |
4.3.3.6 | D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 |
two proteins form a complex that functions as a glutamine amidotransferase, with YaaE as the glutaminase domain and YaaD as the acceptor and pyridoxal 5'-phosphate synthesis domain. Both the glutaminase and synthase reactions are dependent on the respective protein partner. The synthase reaction can also utilize an external ammonium source but, in contrast to other glutamine amidotransferases, is dependent on YaaE under certain conditions |
Bacillus subtilis |
pyridoxal 5'-phosphate + 4 H2O + phosphate |
- |
? |
4.3.3.6 | D-ribose 5-phosphate + glyceraldehyde 3-phosphate + NH4+ |
- |
Plasmodium falciparum |
pyridoxal 5'-phosphate + 4 H2O + phosphate |
- |
? |
4.3.3.6 | D-ribose 5-phosphate + glyceraldehyde 3-phosphate + NH4+ |
- |
Pyrococcus horikoshii |
pyridoxal 5'-phosphate + 4 H2O + phosphate |
- |
? |