EC Number   |
Substrates |
Organism |
Products |
Reversibility  |
|---|
   1.1.1.105 | more |
in addition to all-trans-retinol, RDHE2S recognizes 11-cis-retinol as substrate |
Mus musculus |
? |
- |
- |
| 1.1.1.105 | more |
no activity toward all-trans-retinol is detected using the microsomal and mitochondrial preparations of recombinant murine RDHE2 protein expressed in Spodoptera frugiperda Sf9 cells. But although inactive toward retinol in isolated microsomes, RDHE2 is able to function as a retinol dehydrogenase in intact cells |
Mus musculus |
? |
- |
- |
| 1.1.1.105 | more |
in addition to all-trans-retinol, RDHE2S recognizes 11-cis-retinol as substrate |
Mus musculus C57BL/6J |
? |
- |
- |
| 1.1.1.105 | more |
no activity toward all-trans-retinol is detected using the microsomal and mitochondrial preparations of recombinant murine RDHE2 protein expressed in Spodoptera frugiperda Sf9 cells. But although inactive toward retinol in isolated microsomes, RDHE2 is able to function as a retinol dehydrogenase in intact cells |
Mus musculus C57BL/6J |
? |
- |
- |
| 1.1.1.105 | 11-cis-retinol + NAD+ |
- |
Homo sapiens |
? |
- |
? |
| 1.1.1.105 | 13-cis-retinol + NAD+ |
- |
Homo sapiens |
13-cis-retinal + NADH + H+ |
- |
? |
| 1.1.1.105 | 13-cis-retinol + NAD+ |
RoDH-4 can potentially contribute to the biosynthesis of two powerful modulators of gene expression: retinoic acid from retinol and dihydrotestosterone from 3alpha-androstane-diol |
Homo sapiens |
13-cis-retinal + NADH + H+ |
- |
? |
| 1.1.1.105 | 3,4-didehydroretinol + NAD+ |
60% of the efficiency against all-trans-retinol |
Homo sapiens |
3,4-didehydroretinal + NADH |
- |
? |
| 1.1.1.105 | 5alpha-androstan-3alpha-ol-17-one + NAD+ |
- |
Homo sapiens |
? + NADH |
- |
? |
| 1.1.1.105 | 9-cis-retinol + NAD+ |
higher activity with all-trans-retinol versus 9-cis-retinol |
Mus musculus |
9-cis-retinal + NADH + H+ |
- |
? |
